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A mouth-rinse test that can screen for oral cancer?
This paper presents a promising screening tool for oral cancer – using a simple chlorhexidine mouth-rinse. The hypermethylated ZNF582 and PAX1 markers were chosen based on previous studies using oral scraping methods of collection and have been shown to be...
Socially appropriate part 1: assessing people with TBI
Social communication disorders are one of the most common and yet most under-addressed sequelae of a traumatic brain injury (TBI). Yet speech and language therapists report a lack of assessment tools and a lack of time to fully assess these...
Intracranial complications of otitis media – the difference between kids and adults
Despite a decrease in intracranial complications from otogenic infections since the introduction of antibiotics, there is still morbidity and mortality associated with this. This group from the Netherlands conducted a retrospective review of all the patients treated for intracranial complications...
CRSwNP and smell – is it just the obstruction?
Anosmia and hyposmia are symptoms of CRS both with and without nasal polyps and can significantly affect quality of life. The nature of anosmia/hyposmia is thought to be both sensory-neural and conductive. These authors studied a mouse model in which...
The septum, outside!
Extracorporeal sculpturing of the septum during septorhinoplasty (SRP) is a well-established technique. However, the extent of manipulations of the septum varies amongst authors. In a series of 630 patients undergoing SRP, the authors used a complex extracorporeal septal three dimensional...
Review of surgical treatments of intractable Meniere’s disease
This is a nice summary of the evidence available for the surgical treatments for intractable Meniere’s disease. To summarise, in five-10 years, over 90% of vestibular neurectomy cases, more than 80% of intratympanic gentamycin treatment, and 70-80% of endolymphatic sac...
