You searched for "chemotherapy"

283 results found

Combination PPI and intralesional steroid treatment for recurrent laryngeal granuloma

The existence of a wide range of treatments for recurrent laryngeal granulomas (repeat surgery, high-dose proton pump inhibitor (PPIs), surgery with botulinum toxin injection, botulinum toxin injection alone, etc) is a testament to the refractory nature of this condition, with...

Allergen immunotherapy and allergic rhinitis – EAACI guideline 2017

Allergic rhinitis (AR) is a common chronic childhood disease with considerable social burden and impact on quality of life, frequently necessitating treatment with various combinations of antihistamines and corticosteroids. The allergen immunotherapy (AIT), sometimes known as desensitisation therapy, can modify...

Advances in diagnosis and management of allergic rhinitis

This article reviews advances in the diagnosis and management of allergic rhinitis. Recent advances in the diagnosis of allergic rhinitis include testing of local immunoglobulin E (IgE), urinary test to diagnose aspirin hypersensitivity and optical rhinometry to assess degree of...

Are there benefits of prophylactic swallowing exercises for patients with head and neck cancer?

This randomised controlled trial aimed to establish the impact of prophylactic swallowing exercises in patients undergoing chemoradiation therapy for head and neck cancer. The primary outcome was the functional oral intake scale (FOIS), although secondary measures for feeding tube use,...

In conversation with Professor Paul J Donald

Prof Paul J Donald has recently stepped down as Chairman of the ORL-HN Department at UC Davis in Sacramento and is winding down to retirement. In this interview with Prof Pat Bradley, Prof Donald explains some of the highlights of...

Bevacizumab, NF2, hearing and age

Introduction NF2-related schwannomatosis (NF2-SWN) is an autosomal dominant disorder leading to the development of schwannomas, meningiomas and spinal cord ependymomas. Younger age is a negative prognostic factor. Treatment includes observation, surgery, radiotherapy and medical therapy with bevacizumab (VEGF monoclonal antibody)....

The nice therapist effect: does the therapeutic relationship matter?

Quality of relationships is considered a core component of all speech and language therapy work, yet there is little agreement of what constitutes a therapeutic relationship. This study describes a scoping review to map existing evidence that has investigated this...

Therapeutic alliance: more than the ‘nice person’ effect

Therapeutic relationship is considered a key component of many healthcare interventions, including speech and language therapy. Yet definitions and descriptions of what this concept comprises are ambiguous and sparse. This scoping review used the Joanna Briggs Institute guidelines to guide...

Detecting cancer margins during robotic head and neck cancer surgery using ambient mass spectrometry

We have known about altered metabolism in cancer cells since Otto Warburg described it 97 years ago. But can we take advantage of this knowledge in curing cancer? Jim Higginson explains the value of smoke generated during cancer surgery. The...

Malignancies of the Nasal Vestibule

This text is a comprehensive guide to the management of malignancies of the nasal vestibule. The book starts off with a review of the anatomy, patho-physiology and patterns of disease spread for nasal vestibule carcinomas. Of course, no book on...

Risk factors for loco regional recurrence for oral SCC

Over 250,000 cases of oral squamous cell carcinomas are diagnosed annually worldwide with 128,000 registered deaths. The authors of this study are from a single institution in Germany and have conducted a retrospective audit of 517 patients with oral SCC...

All about velopharyngeal dysfunction

The velopharynx functionally separates the oral from the nasal cavities. Inadequate or abnormal function of this muscular valve affects speech and swallow. Velopharyngeal dysfunction can be subdivided into insufficiency, incompetence and mislearning. This is a review paper and indeed a...