You searched for "inflammatory"

252 results found

Nasal disease and quality of life in athletes

Rhinitis is a nasal condition which is generally underappreciated in primary care and even less in athletes. In this study, the authors specify nasal symptoms constituting rhinitis as nasal blockage, sneezing bouts, rhinorrhoea and itching and compare their prevalence in...

Medication and its effect on the larynx

This article summarises different medications and their effect on the voice. A growing number of patients we see in clinic are on multiple medications that could affect vocal cord function. The author summarises different classes of medications and their potential...

Platelet-rich plasma to reduce post-tonsillectomy haemorrhage and pain

Minimising haemorrhage and promoting healing of raw areas are cornerstones for uneventful and speedy recovery after tonsillectomy. In this single-blinded prospective experimental study, application of platelet-rich plasma to one side tonsillar bed has been compared to the other side in...

Eosinophilic or not eosinophilic: dupilumab seems to work

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a type 2 inflammation with interleukin (IL)-4, IL-13, and IL-5. Tissue eosinophilia in nasal polyps dramatically increased over a 10-20-year period. Classification of the severity of eosinophil status is expected to lead to...

Correlation between middle ear and mastoid volumes with results of type 1 paediatric tympanoplasty

This is a retrospective study of 45 paediatric patients, aged between eight and 18 years, who underwent Type 1 cartilage graft tympanoplasty using conchal cartilage. Middle ear and mastoid volumes of these children were correlated with anatomical and functional outcomes...

Are cardiovascular risk factors associated with hearing loss?

Cardiovascular disease (CVD) risk factors are associated with microvascular damage that can impair molecular transport across capillary walls and cause inflammation and oxidative stress that may damage cochlear structure and function. This study determined, among a population-based sample of Canadian...

A comparison between biologic and surgical treatment (FESS) for chronic rhinosinusitis with polyposis

In recent years, it is being increasingly recognised that chronic rhinosinusitis with nasal polyps (CRSwP) is a type 2 chronic inflammation based on IL-4 and IL-13, and the novel monoclonal antibody, such as dupilumab, is likely to have a major...

Factor favouring the need for revision FESS in chronic sinusitis with polyps – a multivariate analysis including phenotypes

Chronic rhinosinusitis with polyposis is a type 2 inflammation with risks of recurrence and need for revision operations. This is known to depend on the endotype and phenotype factors. This is a retrospective study of 212 patients. Of these, 112...

Is there any point giving postoperative oral steroids after a FESS?

It is well accepted that when medical treatment fails for chronic rhinosinusitis (CRS), endoscopic sinus surgery (ESS) is more effective than continuing with medical therapy alone. A variety of postoperative care options are available, including saline irrigation, in office debridement,...

Sylvester O’Halloran Perioperative Symposium 2024

Co-chair Andrew Dias with best poster winner Nyamateja Kaare. Lisa O’Byrne, ST5 Otolaryngology, St Vincent’s University Hospital, Dublin, Ireland. The annual Sylvester O’Halloran Perioperative Symposium, first held in 1992, has evolved to include all surgical specialties as well as many...

Aetiology, investigation and acute management of sudden sensorineural hearing loss

The cause of a single sided sensorineural hearing loss has a wide variety of aetiologies. This review, by Edwin Halliday, looks specifically at the differential diagnostic causes of a sudden sensorineural hearing loss, the relevant investigations and the management should...

The MACRO Trial: defining best management of chronic rhinosinusitis

A major UK trial in The Lancet finds ESS provides greater symptom relief than long-term macrolides for adults with CRS, supporting earlier surgery and fewer antibiotics. The MACRO Programme was established in 2016 when the UK National Institute of Health...