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Tinnitus treatment device from concept to commercialisation

Innovation in the field of healthcare is fraught with nearly insurmountable challenges. Bringing a novel product to the market requires a new (patentable) idea that can be reduced to practice, manufactured at scale, and can pass all regulatory barriers. In...

Hyposalivation: a review of current and future treatments

Hyposalivation remains a stubbornly difficult condition to treat, but novel therapies may not be far away. Saliva has many essential functions, including aiding digestion and swallowing, lubrication, maintaining tooth integrity and antibacterial activity. When patients experience reduced saliva production (hyposalivation),...

Neuroimaging WG3. Neuroimaging as a window on the heterogeneity of tinnitus

Pim van Dijk and Sven Vanneste describe the hope that brain imaging techniques used for research will provide a better understanding of the heterogeneity of tinnitus through large-scale analysis. Their project will create a procedure whereby researchers can submit their...

Anaesthesia under fire

Kate Prior is an anaesthetist who has, quite literally, been there, done that. In this article she manages to use words on a page to bring to life some of the conditions and challenges she faced as a member of...

The case of the women and the words: intensive therapy can help many years post stroke

Aphasia, a language impairment impacting on a person’s ability to speak, understand, read and write, is most commonly caused by a stroke. Speech and language therapists are trained to work with people with aphasia, often aiming for restitution and rehabilitation...

Urgent call for surgical supplies in Ukraine

The Russian invasion of Ukraine has caused a major shortage of surgical supplies in hospitals. Irina Gout and Peter Cackett are calling for further relief efforts to provide surgical supplies to under-equipped hospitals in Ukraine.

Dysphagia in people with HPV-related oropharyngeal cancer

Human papilloma virus (HPV) associated oropharyngeal cancers are becoming much more prevalent and, in some geographic areas, have overtaken tobacco as the leading cause of oropharyngeal cancer. HPV-associated cancers are also reported to have better prognosis in general, and research...

Intraoperative MRI use during pituitary tumour resection

This article provides an overview of intraoperative MRI (iMRI) use in transphenoidal surgery (TSS) for pituitary tumours. Traditionally imaging of the surgical field during surgery involves intraoperative fluoroscopic imaging or neuronavigation which help to avoid injury to critical structures but...

Oropharyngeal malignancies

The authors retrospectively reviewed 44 patients who underwent a combined transoral and transcervical treatment without mandibulectomy for oropharyngeal malignancy. The combined approach was performed first by a neck dissection followed by transoral excision of the lesion and reconstruction by a...

Lymph node metastases in papillary thyroid cancer

This retrospective Korean cohort study looked at the risk factors associated with bilateral lateral lymph node metastases in patients with unilateral papillary thyroid cancer. There were 11 patients who met the inclusion criteria across an 11-year period from 2009 to...

Factors affecting the occurrence of salivary fistula after total laryngectomy

It is generally believed that patients should be fed by nasogastric tube for 7-10 days after undergoing total laryngectomy or laryngopharyngectomy to avoid the occurrence of post-operative salivary fistula. This study challenges this belief and looks into various factors that...

Outcomes of reirradiation for recurrent head and neck SCC

Recurrent squamous cell carcinoma of the head and neck is often a challenge to manage when radiotherapy has previously been administered as a component of the initial treatment. Salvage surgery is usually the preferred modality of treatment, but for unresectable...