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Sudden sensorineural hearing loss – who will get better?

Idiopathic sudden sensorineural hearing loss (ISSNHL) is a rare but potentially devastating condition. For patients presenting with this condition, prognosis is of paramount importance. Wu et al begin to address this issue by retrospectively studying 17 potential prognostic factors for...

Vascular disease and sudden sensorineural hearing loss

Oussoren et al performed a systematic review and meta-analyses of current literature on the above topic: specifically, cardiovascular risk factors for developing idiopathic sudden sensorineural hearing loss (iSSNHL), the presence of white matter hyperintensities in patients with iSSNHL and the...

Adjuvant radiotherapy for T4N0 laryngeal cancers treated with laryngectomy

A total laryngectomy remains the gold standard for the initial treatment of advanced (T4) squamous cell carcinomas of the larynx without evidence of distant disease. Adjuvant radiotherapy (RT) is also recommended for such cancers. In the absence of other adverse...

Bones, stones and surgical moans: rethinking PTH dynamics in parathyroid surgery

Intraoperative parathyroid hormone (IOPTH) testing has revolutionised minimally invasive unilateral parathyroidectomy (MIP) as the gold standard treatment for primary hyperparathyroidism, replacing old-timey four-gland exploration. IOPTH testing ensures reliable excision of all hypersecreting glands, including those pesky hard-to-find ones, without relying...

Are you still talking about Covid?

Bell’s palsy (idiopathic facial nerve palsy) has an annual incidence of 15 to 30 cases per 100,000 people. This study aims to assess the effect of Covid and Covid vaccination on this incidence using a large database. Authors used TriNetX,...

Modernising scientific careers and audiology in the United Kingdom

Modernising Scientific Careers (MSC) is an education and training strategy for 51 disciplines in healthcare science within the National Health Service (NHS) in the United Kingdom (UK). Some of these disciplines lacked clear training routes as well as registration opportunities...

Mind the gap – developing a sustainable pipeline for hearing therapeutics

In this article, the authors describe three key challenges faced in developing hearing therapeutics. Collaboration between companies, sectors and disciplines will be key to finding solutions. The unmet need for therapies for hearing loss grows apace, with prevalence rising across...

Recent advances in the diagnosis of silent reflux

The vexed topic of reflux always generates much discussion, particularly when it comes to testing. We hear about a non-invasive assay that is gaining in popularity. Voice disorders impact around four percent of the UK population and can significantly hamper...

Early injection laryngoplasty for iatrogenic vocal fold movement impairment – a safe and effective treatment

This Ed’s Choice examines the role of early injection laryngoplasty on swallowing dysfunction and is one of a few studies available in the literature. Research on early injection laryngoplasty has been predominately focused on voice and reducing the risk of...

British Skull Base Society Clinical Consensus Document on Management of Head and Neck Paragangliomas (HNPGLs)

All forms of HNPGLs should be managed by a multidisciplinary team (MDT) of core members from skull base otolaryngology, head and neck surgery, clinical genetics, oncology, endocrinology, vascular surgery, radiology and pathology. Extended members include neurosurgery, endocrine surgery, nuclear medicine,...

Rapid, non-invasive and differential diagnosis of laryngopharyngeal reflux

Laryngopharyngeal reflux (LPR) is a significant condition that frequently goes undiagnosed at a primary care level, resulting in patients being unnecessarily referred to secondary care with symptoms such as a sore throat, persistent cough, vocal problems and issues with swallowing.

Recruitment of Sudden Hearing Loss Patients for Clinical Trial: Novel Compound AC102 Outperforms Corticosteroids Preclinically

While corticosteroids are widely used to treat Sudden Sensorineural Hearing Loss (SSNHL), there is still no therapy with proven efficacy and regulatory approval for this debilitating condition.