This review paper analysed studies published between January 2000 and January 2024, assessing the functional outcomes of total glossectomy combined with laryngectomy. The primary outcomes included speech ability, swallowing function and gastrostomy tube dependence. Secondary outcomes considered were disease recurrence at one year and average survival time following surgery. A total of 748 non-duplicated articles were identified, with seven studies meeting the inclusion criteria, collectively reporting on 92 patients who underwent the combined surgery. Swallowing ability was assessed in 60 patients, with 53.3% able to safely consume an oral diet. Among 66 patients, eight (12.1%) retained some level of functional speech, though only half of these achieved quality speech. Disease recurrence occurred in 52% of cases, and pooled data from the studies indicated a mean survival time of approximately 21 months. The authors emphasise the importance of open and transparent discussions with patients regarding both functional and oncological outcomes. They also highlight the role of rehabilitation strategies, particularly speech and language therapy as well as dietary support, in postoperative care. Notably, reconstruction was not addressed in the assessment of outcomes, despite its potentially limited value.
Total glossectomy and laryngectomy
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