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Biologicals for severe chronic rhinosinusitis with nasal polyps. Any use?

Recent advances and knowledge of inflammatory endotypes of chronic rhinosinusitis with nasal polyps (CRSwNP) led to introduction of biological agents such as monoclonal antibodies targeting IgE (omalizumab) and Interleukins (ILs) such as IL4R alpha (dupilumab) and IL5. The European Academy...

Long-term effectiveness of sleep surgery for obstructive sleep apnoea

n this study, 39 patients from Turkey with obstructive sleep apnoea (of varying severity) underwent an expansion sphincter pharyngoplasty. This operation was devised by Prof Kenny Pang in Singapore and involves using the palatopharyngeus muscle and partly relocating it laterally...

Global incidence of sporadic vestibular schwannoma

The incidence rate of sporadic vestibular schwannoma (VS) has commonly been quoted as one in 100,000. However, since the advent of screening for asymmetrical hearing loss and increased availability of modern MRI scanning, more recent studies have shown the incidence...

Sudden sensorineural hearing loss – who will get better?

Idiopathic sudden sensorineural hearing loss (ISSNHL) is a rare but potentially devastating condition. For patients presenting with this condition, prognosis is of paramount importance. Wu et al begin to address this issue by retrospectively studying 17 potential prognostic factors for...

I saw it on the internet: gathering evidence for clinical decision making

Evidence-based practice is often described as the integration of three sources of information to inform clinical practice, namely: 1) research evidence/practice guidelines; 2) client preferences/needs, and: 3) clinical experience. Speech and language therapists have reported a lack of time and...

Tonsillectomies are a pain in the neck!

You thought tonsilitis was bad? Having your tonsils removed, now that’s a hard pill to swallow. Very well, you’ll no longer have to fear the CENTOR, but how do we make recovery as pain-free as possible? Pantabtim and colleagues set...

Swallowing the risk: managing dysphagia in aged care

The risk of dysphagia increases with age and the prevalence of dysphagia in aged care facilities is 41–52%. Dysphagia increases the risk of aspiration, asphyxiation, malnutrition, pneumonia and ultimately death. Modifying food and fluids, by providing mashed or pureed foods...

Hear me out – tiny steroid implants for fighting meningitis-induced deafness

Sensorineural hearing loss is the most common neurological complication of pneumococcal meningitis. Bacterial infiltration into the inner ear triggers inflammation, leading to cochlear fibrosis and sclerosis – damage that, in over a third of cases, affects both ears. Current Infectious...