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Immunosuppresants and ototoxicity

There is a wide range of immunosuppressant drugs ranging from calcineurin inhibitors (e.g. cyclosporine), anti-folic agents (e.g. methotrexate) to anti-TNF and monoclonal antibodies, many of which could be ototoxic. The authors performed a systematic review assessing ototoxicity secondary to immunosuppressant...

Atlas of Ear Diseases

In this self-published atlas, the author has approached the external ear and middle ear pathologies on the basis of classification of diseases, emphasising the added benefits of using of an oto-endoscope in identifying the external and middle ear pathologies. The...

Metaplasia of the concave septum

This group conducted a one year prospective study and sampled mucosa from 42 randomly selected patients with septal deviation at a single centre. They found significantly higher rate of squamous metaplasia and lymphocytic infiltration in septal mucosa on the concave...

Malignant change of pleomorphic adenoma

Pleomorphic adenoma is the most common salivary gland tumour. The potential to undergo malignant transformation is rare but well described. The authors of this article present a case report of metastasis where the preceding submandibular gland pleomorphic adenoma preserves its...

Sublingual gland tumour resection

This paper from South Korea analyses the pathology arising from 20 malignant sublingual gland tumours. Adenoid cystic carcinoma followed by mucoepidermoid carcinomas were the most common. Tumour invasion into the lingual nerve was detected in 40% of cases, and into...

Tactile Sensing and Displays: Haptic Feedback for Minimally Invasive Surgery and Robotics

This book has a catchy title and due to my interest in developing simulation systems for training in surgery I was delighted to be asked to review. However, I found it very hard going and the first few chapters are...

Is a chest x-ray necessary in making urgent referrals for suspected head and neck cancer?

The article presents an audit on urgent referrals for suspected head and neck cancer in 2144 patients. Only 8.6% of cases proved positive for head and neck cancer. The Scottish Referral Guidelines were adhered only in 55.1% of cases. Interestingly,...

Is it worth paying for group therapy?

Group therapy for post-stroke communication difficulties has been described in the research literature for more than 50 years and is generally considered an efficacious approach. Yet these authors express concern that the American Medicare system is less willing to fund...

What is the prognostic value of lymph node yield and density in head and neck cancer?

Neck dissection in addition to surgery of the primary site is commonly recommended in head and neck cancer treatment. However, there has been no consensus on the number of nodes that need to be removed to constitute a sufficient neck...

The push towards scarless parotid surgery

When dealing with benign parotid pathology, high expectations are placed on the operating surgeon to preserve key neurovascular structures, especially the animating facial nerve, through meticulous dissection. With time, there has been a greater emphasis on improving cosmesis in parotid...