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Immunosuppresants and ototoxicity
There is a wide range of immunosuppressant drugs ranging from calcineurin inhibitors (e.g. cyclosporine), anti-folic agents (e.g. methotrexate) to anti-TNF and monoclonal antibodies, many of which could be ototoxic. The authors performed a systematic review assessing ototoxicity secondary to immunosuppressant...Current practice in cochlear implantation
From candidacy to surgery and rehabilitation, cochlear implant practice is evolving, with new technologies shaping outcomes for patients worldwide. Image courtesy of MED-EL. Cochlear implants restore a sense of hearing in the profoundly deaf, representing the most successful neuroprostheses available,...What’s new in genetic testing for hearing impairment?
Often the first question following the diagnosis of a hearing loss is ‘why?’ In this article Ali Danesh explores the advances made in uncovering ‘why’ from a genetics perspective. Ali describes the panel of genetic tests now commercially available to...‘The Sun does not forget a village just because it is too small’ – African proverb
Solar powered hearing aids In the middle of the morning of January 24, 2002, I had been in Otse for only three days, a village of 3500 in the south of Botswana, when I heard a knock at the door....
Outcomes of larger glottic cancer volumes treated with radiotherapy
T3 glottic cancer is characterised as vocal cord fixation and/or invasion into pre-epiglottic, post-cricoid, paraglottic spaces and/or within the inner cortex of thyroid cartilage. Traditionally, laryngectomy was considered the primary option to treat T3 laryngeal glottic cancers until other options...
Patients with severe uncontrolled CRSwNP respond to biologics in the real world
Clinical trials have demonstrated that biologics are effective in treating patients with chronic rhinosinusitis with nasal polyps (CRSwNP). This multicentre (15 tertiary care centres in France) observational prospective cohort study aims to examine the effectiveness of biologics in treating CRSwNP...A new Armed Forces Tinnitus Hub
Tinnitus UK has partnered with the Veterans Welfare Group (VWG) to launch an online hub designed to support veterans, service personnel, and their families living with tinnitus.
Grading dysphagia as a toxicity in treating head and neck cancer
Common Terminology Criteria for Adverse Events (CTCAE) is a system used by clinicians to grade the toxicity of oncology treatments in a standardised manner. Dysphagia is perhaps the most common long-term toxicity of head and neck cancer treatment. Currently, a...
Do steroids improve outcome in acute vestibular neuritis?
The role of steroids in short and long-term recovery from acute vestibular neuritis has been a subject of debate for several years. The authors reported findings of a prospective randomised trial in 60 adult patients. Inclusion criteria were acute vertigo...Genomic testing for deafness and its implications
Gene therapies for hearing loss are rapidly advancing and will be transitioning to clinical practice. Here, the authors explain why clinicians involved in managing these disorders need to be aware of these advances. Genomic testing in England was significantly reconfigured...
Total Otolaryngology - Head and Neck Surgery
This single volume, 1098 page book with 667 illustrations, covers all aspects of otolaryngology in both theory and practice. Compiled together by a team of world renowned co-editors from North America, as well as authors from differing specialities, this book...
