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Genetics of IP-III
The authors provide a literature review of the genetic basis and clinical features of incomplete partition (IP)-type III. The condition is seen typically in males and is due to mutation in the POU class 3 homeobox 4 (POU3F4) gene which...Harnessing head and neck cancer genomics for personalised medicine
Luc Morris updates us on the future of cancer diagnosis and treatment, which lies in “personalised oncology”, where specific molecular alterations of each tumour will be identified, and matched with actionable alterations in existing therapies, ushering in the era of...Hearing about genes
I have been fortunate in my career to travel as an invited lecturer at many hospitals, universities and professional societies around the world. I have spoken to audiology societies, otolaryngology societies, and university communication disorders programmes in Europe, Asia, Africa,...
NSC- HHT – a systematic review of intranasal Bevacizumab
This systematic review of 13 studies concerning the use of an anti-angiogenic nasal treatment in the management of epistaxis in HHT patients finds no significant effect. This paper looked at four RCTs, three prospective studies, three retrospective, one case series...Innovative approaches to treating deafness
Shahar Taiber and Karen Avraham give us a summary of gene therapies for hearing loss, with an overview of limitations and what the future holds. Hearing loss is the most common sensory disorder. The last two decades have seen a...
Outcome measures for hearing loss
This short editorial explores some possible options in measurement of quality of care in audiology. We traditionally tend to use clinician-related outcomes in place of patient-reported outcome measures and so we could miss a wealth of data on the impact...
Precautions to be taken in cosmetic facial surgery
In this comprehensive write-up on precautionary measures to be taken when doing cosmetic surgery on our patients, the authors begin by emphasising that facial plastic surgery is no longer limited to celebrities and the privileged. It has extended into everyday...When patient choice stands in the way of patient-centredness
In the field of hearing care, there is increasing focus on ensuring patient autonomy and choice. Greater participation in decision making is supposed to result in better patient satisfaction. A study conducted in ENT and audiology clinics paradoxically suggests that...AI reshaping the landscape of head and neck cancer
With artificial intelligence set to transform almost every aspect of life, Abishek Mahajan reviews its potential to improve head and neck cancer care. Artificial intelligence (AI) has emerged as a transformative tool in healthcare. In the realm of oncology, AI...The future of rhinology: What will come first, a radical change in rhinological management or the decimation of the world?
In this article, Simon Gane looks forward to what the future holds, on the presumption he survives. Setting aside the questions of the UK even existing, the NHS still working, or the fact we’ll be commuting to our jobs in...
Case study suggesting mtDNA mutation as a tinnitus factor: ND1:m.3394T>C
Konadath et al report a genetic case study of a 24-year-old female experiencing reduced hearing sensitivity and tinnitus along with a blocked sensation in her right ear, sudden onset one year prior with no other otological complaints. Standard audiometry along...
