You searched for "disease"

1618 results found

Outcomes of reirradiation for recurrent head and neck SCC

Recurrent squamous cell carcinoma of the head and neck is often a challenge to manage when radiotherapy has previously been administered as a component of the initial treatment. Salvage surgery is usually the preferred modality of treatment, but for unresectable...

Dysplasia at the margins of laryngeal cancer specimens following laser resection – is conservative management appropriate?

Transoral laser microsurgery (TOLM) remains the cornerstone of treatment for early laryngeal squamous cell carcinomas. Whilst the hope is always to achieve a complete surgical excision with clear margins, it is sometimes the case that on histological analysis, disease is...

Canal cholesteatoma

This is a retrospective study of patients with external auditory canal cholesteatoma (EACC) managed at a single tertiary centre from 1 January 2010 to 1 January 2021. Ninety patients (100 ears) were included. Mean age at diagnosis was 56+23 years....

Peptest Q&A

Untreated reflux can cause inflammation, scarring, narrowing and precancerous changes in the oesophagus and larynx, and may increase the risk of asthma and sleep apnoea.

KTP laser ablation for early glottic cancer

TLM for glottic carcinoma has historically been performed with a carbon dioxide (CO2) laser. A much smaller literature base has examined the use of potassium titanyl phosphate (KTP) laser in this context. This retrospective chart review aims to fill that...

Gardasil vaccination as an adjuvant treatment for established recurrent laryngeal papillomatosis in male adults - does it stimulate an immune response?

Recurrent respiratory papillomatosis (RRP) is well known to be caused by infection with the human papilloma virus (types 6 and 11). Recurrence after surgical removal is common and potentially frequent and severe. Previous research has established that many patients with...

HPV and ENT; should we vaccinate boys?

David Black and Charlie Hall reiterate Vin Paleri’s pleas for a common sense evidence-based approach by those who allocate healthcare resources to the now urgent issue of HPV-related disease. They discuss the merits of different vaccines and the need for...

Otology, Neurotology and Skull Base Surgery Book Review

This concise pocket-sized textbook aims to provide a practical reference that clinicians can use in every day otological and skull base practice. The senior author, Derald Brackmann, is one of the leading neurotologists of the modern era and, together with...

Quality of life after cochlear implantation in the older population

Cochlear implants (CI) have been increasingly adopted in older adults with severe to profound hearing loss as a result of the growing and ageing world population. There is much interest in the cost-effectiveness and quality of life in CI users....

What’s new in genetic testing for hearing impairment?

Often the first question following the diagnosis of a hearing loss is ‘why?’ In this article Ali Danesh explores the advances made in uncovering ‘why’ from a genetics perspective. Ali describes the panel of genetic tests now commercially available to...

Universal newborn hearing screening: a global health perspective

Intuitively, as health professionals, we know that universal newborn hearing screening (UNHS) makes sense. Bolajoko Olusanya outlines how UNHS fits in with global health priorities, as well as illustrating how such programmes can help to deliver additional benefits to communities....

From the editor SepOct 2021

As the pandemic evolves, the world seems to be divided into those countries that are fortunate enough to have good vaccine coverage and, hence, are able to open up their societies; and those who do not have an adequate vaccine roll-out and are having to live with significant restrictions or high levels of prevalent disease.