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CRSwNP initiation, not always an interleukin fault
CRSwNP, similar to asthma, is an inflammatory disorder (type II) with eosinophilia and raised IL-5 and IL-13. Inflammation in CRSwNP is thought to be started by IL-25, IL-33 and thymic stromal lymphopoietin (TSLP), all of which form an important part...
Salvage surgery vs. repeat stereotactic radiosurgery for progressing vestibular schwannomas
This large multicentre case series of patients treated twice with stereotactic radiosurgery (SRS) for progressing vestibular schwannomas (VS) is reported by the International Gamma Knife Radiosurgery consortium. Progression of tumour growth after primary SRS is rare but does occur. Complications...
Possible correlation of ABR changes with prognosis in sudden sensorineural hearing loss
A sensorineural hearing loss (SNHL) of 30dB or more affecting at least three frequencies and occurring over less than three days is classified as ‘sudden’ SNHL (SSNHL). Treatment is urgently undertaken with systemic and/or intra-tympanic steroids, and ijn some cases...
Long-term curative effects of microvascular decompression for hemifacial spasm
This article describes results of a multicentre prospective trial performed to evaluate long- and short-term outcomes and complications of patients who underwent microvascular decompression (MVD) for hemifacial spasm (HFS). The surgeries were performed by surgeons with more than 15 years...
Tympanostomy tubes outcomes by tympanic quadrants- a meta-analysis
Tympanostomy tube (TT) insertion is one of the most common ENT procedures, resulting in millions of TTs being implanted per annum and occurring complications that need to be addressed. Premature TT extrusion (PTTE) is a well-recognised such complication, affecting almost...
Early DCR may be better than delayed in acute dacrocystitis?
Traditionally, acute dacrocystitis has been treated conservatively with antibiotics, analgesia and warm compresses, with surgery reserved for later when the infection has subsided. This meta-analysis looks at early vs. late endonasal dacrocystorhinostomy (DCR) in the treatment of acute dacrocystitis, looking...
Tubomanometry in eustachian tube dysfunction
This prospective study evaluated the validity and reliability of tubomanometry (TMM) in 25 patients with sinus disease, 75 patients with middle ear disease and 25 healthy volunteers. After thorough clinical examination, the participants were evaluated with TMM, nasal endoscope, otoendoscope,...
Talk your brain well: discourse training to fortify your cognitive functioning and protect against dementia
Mild cognitive impairment (MCI) can be described as a transitional stage prior to a diagnosis of dementia. Approximately 15% of people with amnestic MCI (where memory is the leading symptom) develop dementia. Nonpharmacological interventions, specifically cognitive training, has shown some...
