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Systemic agents in thyroid cancer

For those patients who have disseminated or unresectable thyroid cancer, Dr Arabella Hunt and Dr Kate Newbold review systemic treatments, their differences, toxicities and outcomes. Thyroid cancer is the most common endocrine malignancy. It is subdivided into differentiated (papillary, follicular...

Aetiology, investigation and acute management of sudden sensorineural hearing loss

The cause of a single sided sensorineural hearing loss has a wide variety of aetiologies. This review, by Edwin Halliday, looks specifically at the differential diagnostic causes of a sudden sensorineural hearing loss, the relevant investigations and the management should...

Discovery in the genetics of complex disease: Otitis media

Otitis media (OM), a common disease of childhood, is considered to be a complex trait with multiple genetic and environmental factors expected to contribute to a child’s risk of developing recurrent acute OM (rAOM; ≥3 episodes in 6 months or...

NHS collaboration and partnership with the pharmaceutical and medical devices industries

Historically the relationship between industry and the NHS has been a cautious one. Both sides have typically worked with only partially disclosed agendas, under a pervading fear of finding themselves on the wrong end of a win-lose negotiation. Things have...

Giacomo Puccini’s laryngeal cancer

Giacomo Puccini, one of the best known composers of all time, was diagnosed with laryngeal cancer and died from the disease in 1924. In this article, Rosario Marchese-Ragona and Alessandro Martini describe Puccini’s experience of the disease with quotes from...

Endoscopic ear surgery in children

The benefits of endoscopes in otologic surgery, which have become increasingly widely appreciated in recent years, are very well suited to the management of paediatric middle ear disease. Although one might imagine that the smaller ear canal of a child...

Adolescence, drug use and body image

Teenagers are notoriously conscious of how they are perceived by others. Dr Saraiva and colleagues explain how this can lead to problems with substance abuse for both boys and girls, and discuss the different substances they may encounter. Adolescence is...

Tonsillectomy in adolescents

Tonsillectomy is one of the most common operations performed across the developed world. Salil Sood and Ray Clarke discuss the special considerations that apply when performing this procedure on adolescent patients. Tonsillitis in teenagers can be exceptionally painful and disruptive....

Audiological evaluation and management of teenagers with tinnitus

There is a growing interest in investigating, understanding and managing tinnitus in children and adolescents, with several articles on the subject published in journals over the last year. Brian Fligor describes the approaches to consider when discussing tinnitus with teenagers....

Airway stenting in paediatric ENT

Although experience in the use of airway stents in adults is considerable, their use in children is more recent and more limited. Cláudia Schweiger and Michael J Rutter provide an overview of stents and their use in paediatric airway. Stenting...