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Precision and personalised genomic and epigenomic medicine in audiology/hearing loss

A detailed look at the pathogenesis of acquired hearing loss due to exposure to ototoxicity during pregnancy or shortly after birth. Insights from genomic medicine have shown that, along with environmental factors causing epigenetic alterations, hearing loss may be caused...

Neuromodulation in drug resistant epilepsy

Treatment of epilepsy can be considered generally as medical or surgical. Anti-epileptic drugs achieve a five-year seizure freedom in 54-70% patients. It is estimated that 50-90% of patients with drug-refractory epilepsy may not be candidates for resective surgery. For example,...

What we need to know about the new frontier of inner ear therapies

This is an interesting and topical review of the emerging biotechnology and pharmaceutical solutions for hearing loss and related conditions such as tinnitus. This paper suggests we are on the cusp of a very large step-change in the way we...

Are we screening enough? Genetics in adult-onset sensorineural hearing loss

Sensorineural hearing loss (SNHL) in adults can be a result of multiple factors such as age, noise exposure and autoimmune pathology. In a group of patients, no cause is identified and the SNHL is treated as idiopathic. Authors evaluate the...

Anticoagulated patients and epistaxis

This systematic review looks at the increasing complexity in this space as anti-thrombotics become more sophisticated and move away from the more well understood management of warfarinised patients. After a thorough search, 29 papers were found to be relevant and...

Storytelling is good for your memory

Mild cognitive impairment (MCI) presents a challenging frontier in healthcare due to the limited availability of effective drugs. Despite its prevalence and potential progression to dementia, there remains a notable gap in pharmacological interventions targeting MCI. This month’s Editors’ Choice...

Handbook of Otolaryngology, Head and Neck Surgery – Second Edition

The authors and contributors of this book have done a stellar job of updating the content while maintaining the portability essential for any ‘handbook’. They begin with a sound introductory section which presents a comprehensive road map to evaluating the...

To make a difference

Education and training have a key part to play in the development of leaders of the future; Dorte Hammershøi discusses the educational approaches taken in Denmark and the pros and cons of the methods used. Dorte also explains the BEAR...

St Blaise - patron saint of the throat

In a previous article, we looked at some interesting legends surrounding patron saints of the ear and hearing [1]. As we celebrate the Feast Day of St Blaise of Sebastia on 3 February, we hear some fascinating tales and myths...

The role of artificial intelligence and applications in ENT surgery

AI is progressing apace. If you’re wondering how it might affect our working lives in ENT, read on for insights and a pilot study that show us what may be possible. The recent launch of ChatGPT, an open access artificial...

Why does music move us? Music as auditory signals of emotion

Music forms an integral part of the lives of people in all known cultures around the world. In this article Dr Sandra Garrido explains that in fact, our response to music is largely innate and is related to the evolutionary...

Using psychological behaviour change theory in vestibular practice

Fiona Barker explains the importance of recognising and understanding how habitual behaviours in vestibular patients can affect treatment outcomes, and how we as audiologists can support and encourage patients to modify these behaviours and perhaps address our own professional behaviours...