You searched for "trial"

1454 results found

Is there any point giving postoperative oral steroids after a FESS?

It is well accepted that when medical treatment fails for chronic rhinosinusitis (CRS), endoscopic sinus surgery (ESS) is more effective than continuing with medical therapy alone. A variety of postoperative care options are available, including saline irrigation, in office debridement,...

Pharmacologic treatment options for tinnitus

This article summarises potential medications that could be used to treat tinnitus and the evidence behind their use. Effective medications to eliminate tinnitus remain elusive but treatment could be divided into two broad categories: treatment to reduce perception of tinnitus...

Outcomes in rhinosinusitis

This review goes through the various different ways of assessing outcomes and describes the pros, cons and limitations of each. The different methods are described in the context of guidelines in diagnosis and management and compared with other conditions such...

Are we making progress on tinnitus?

One of the aspects of tinnitus that drew me into it becoming a major theme of my clinical and research work was how little work had been done when I began to see patients in the mid 1980s. This struck...

Management of postoperative cholesteatoma

This prospective longitudinal observational study compared the ability of second-look surgery with that of surveillance using serial non-echo-planar diffusion-weighted imaging to detect residual cholesteatoma after canal wall-up mastoidectomy. A total of 34 patients were included in the study who underwent...

Do ENT surgical patients need VTE prophylaxis?

In the UK, current NICE guidance for venous thromboembolism (VTE) prevention does not give specific advice about patients undergoing otolaryngology/head and neck surgery (OHNS). This systematic review provides up-to-date information based on available, although limited, evidence about the incidence of...

What can we tell about swallow physiology from a bedside clinical assessment?

Knowledge about swallowing physiology has greatly increased with the use of instrumental assessments such as videofluoroscopy (VFS). The authors of this paper performed an analysis of data obtained from 60 stroke patients who were assessed via a clinical swallow examination...

Contemporary UK experience of oropharyngeal transoral laser microsurgery

It is well recognised that the current emergence of HPV-positive oropharyngeal squamous cell carcinoma (OPSCC) as a distinct disease entity requires a fresh look at standard treatment modalities that are based on chemoradiotherapy for stage III/IVa OPSCC. The Newcastle experience...

Impact of the updated cancer staging system on HPV-positive disease

The AJCC cancer staging manual was updated in 2017 (8th edition). It is used in the MDT setting for planning treatment and assessing prognosis for individual patients, and is also widely used internationally in clinical trials. Unlike previous iterations of...

The debate: endoscopic vs microscopic ear surgery – meta-analysis of outcomes

Although the endoscopic approach to ear surgery has become more common in clinical practice, the debate about its role versus the traditional microscopic approach continues in many ENT units. This meta-analysis from the Mount Sinai ENT department in New York...

Double layer graft in endoscopic tympanoplasty

This Turkish retrospective study looked at the success rates following endoscopic tympanoplasty using the double layer graft technique. This involves using a tragal cartilage and perichondrium composite graft and a separate perichondrial graft for closure of the perforation. The crescent...

Combined use of a hearing aid and a cochlear implant: a case study

When multi-channel cochlear implants (CIs) were first introduced in the 1980s, their use was restricted to people who derived no benefit from conventional amplification. Over the past three decades, however, the criteria for CIs has been relaxed considerably, and it...