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The changing spectrum of cancer of the oropharynx: dilemmas and future directions

The association of HPV in oropharyngeal cancer has identified a ‘new disease’, with its unique biologic behaviour, and challenges for clinicians in selecting therapeutic combinations offering maximum efficacy and minimum morbidity or long-term sequela currently under study in clinical trials....

Dysphagia in people with HPV-related oropharyngeal cancer

Human papilloma virus (HPV) associated oropharyngeal cancers are becoming much more prevalent and, in some geographic areas, have overtaken tobacco as the leading cause of oropharyngeal cancer. HPV-associated cancers are also reported to have better prognosis in general, and research...

Oral Cancer: Symptoms, Management and Risk Factors

This publication is edited by internationally renowned Professor of Otolaryngology, Head and Neck Surgery, Sheng-Po Hao, in the School of Medicine, Fu-Jen University, Taipei, Taiwan. He has organised contributors from many countries, many of whom also work in Taiwan, where...

Laryngeal Cancer: Clinical Case-Based Approaches

This book, published by Thieme, provides a lot of information in a compact size. I enjoyed reading the book as it has an international list of authors and contributors from South America, USA, Europe and Asia which gives it an...

Difficult consultations with HPV-positive oropharnyeal cancer patients

The aetiological role of human papillomavirus (HPV) in oropharyngeal squamous cell carcinoma (OPSCC) is well established, and its incidence has massively increased over the last decade, whilst the incidence of HPV-negative OPSCC is declining. Although we know that HPV-positive OPSCC...

A time-saving method for faster cancer diagnosis and treatment

One of the main impediments in achieving UK Government cancer diagnosis and treatment targets is lack of diagnostic capacity. An increase in head and neck cancers by 50% in the last five years has put on additional strain. In this...

Head and neck cancer recurrence: a prospective analysis

The ‘cancer journey’ is synonymous for many individuals worldwide with frequent post-treatment hospital visits where the spectre of possible recurrence hangs over the consultation. This is a prospective analysis of 401 follow-up visits in Melbourne, Australia looking at follow-up in...

Harnessing head and neck cancer genomics for personalised medicine

Luc Morris updates us on the future of cancer diagnosis and treatment, which lies in “personalised oncology”, where specific molecular alterations of each tumour will be identified, and matched with actionable alterations in existing therapies, ushering in the era of...

Patient initiated follow-up in head and neck cancer

Is it time for a change in the way we follow up head and neck cancer patients after treatment? Paul Nankivell and Hisham Mehanna explain the rationale for the PETNECK2 trial. After completion of curative intent treatment, clinical follow-up currently...

Transnasal oesophagoscopy in head and neck cancer: an update

The role of transnasal oesophagoscopy (TNE) in the management of head and neck cancer patients is evolving. Until 1990, oesphagoscopy required specialist endoscopists, general anaesthesia or sedation. This review succinctly summarises updates in the evidence for TNE in: i) Screening...

Significance of abnormal retropharyngeal nodes in head and neck cancer

Abnormal retropharyngeal lymph nodes (RLN) have prognostic relevance for patients with oral, oropharyngeal or nasopharyngeal squamous cell carcinoma (SCC). However, consensus on the evaluation and management of abnormal RLN in these patients is lacking. The authors of this paper provided...