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Peptest Q&A

Untreated reflux can cause inflammation, scarring, narrowing and precancerous changes in the oesophagus and larynx, and may increase the risk of asthma and sleep apnoea.

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In laryngopharyngeal reflux (LPR), refluxed stomach contents travel up the oesophagus and reach the larynx, causing chronic extra-gastrointestinal symptoms such as a persistent cough, hoarseness or difficulty swallowing, meaning it is often attributed to ENT problems.

Streamlining ENT pathways

Laryngopharyngeal reflux (LPR) may present with severe extra-gastrointestinal symptoms – including a persistent cough, vocal problems, asthma or difficulty swallowing – that can be incorrectly attributed to ENT problems because patients and GPs alike assume they stem from colds, allergies or over-using the voice.

Reza Band<sup>®</sup> UES Assist Device

Members of the ENT and Audiology News team spoke to Rose Henrichs, Solutiones Vobis and Nick Maris, CEO and President of Somna Therapeutics about the Reza Band device. Nick Maris. Rose Henrichs. What is your involvement in Reza Band? And...

A histological test for LPR?

Laryngopharyngeal reflux (LPR) is often considered to be a contributory factor to the development of a spectrum of laryngeal abnormalities including vocal cord leukoplakia and dysplasia. This is especially the case when traditional risk factors, such as tobacco smoking, are...

Pepsin detection in the diagnosis of LPR: New webinar available on-demand

BIOHIT HealthCare has staged an on-demand webinar about the clinical application of pepsin measurement in the investigation of reflux.

Helicobacter pylori and chronic tonsillitis

Helicobacter pylori infection in the stomach has long been associated with chronic gastritis, duodenal and peptic ulceration and even gastric cancer. Whether laryngopharyngeal reflux (LPR) brings up these organisms and induces chronic tonsillitis is an interesting concept, which the authors...

Bile acids and pharyngeal malignancy

Laryngopharyngeal reflux is a commonly described condition. There is strong evidence linking gastro-oesophageal reflux with oesophageal carcinomas. Gastric refluxate consists of gastric acid, pepsin and bile acids. The roles of pepsin and acidic conditions in the development of laryngopharyngeal carcinoma...

The era of lateral flow tests in ENT

The COVID-19 pandemic brought to light the versatility of lateral flow tests (LFTs), with heavy endorsement from healthcare professionals and a greater awareness among the general public.

Laryngeal oedema as a side-effect of tyrosine kinase inhibitor therapy

Tyrosine kinase inhibitors (TKIs) such as Imatinib are increasingly being used to treat haematological and solid malignancies. These agents have revolutionised the treatment of chronic myeloid leukaemia in particular. Although better tolerated than most conventional chemotherapy drugs, multiple side-effects have...

Association of childhood OME with obesity

Many factors influence the development of otitis media with effusion (OME) in children, some of them being increased plasminogen factor inhibitor (PAI-1) levels, eustachian tube obstruction and gastro-oesophageal reflux. These factors are also associated with obesity. Sixty children with mean...

Is GERD linked to CRS?

We are all well aware that both chronic rhinosinusitis and reflux are prevalent in our populations. This meta-analysis looked at 25 studies investigating the association between GERD, LPR and CRS, therefore evaluating more than 117,000 patients. The results are fascinating...