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Detecting cancer margins during robotic head and neck cancer surgery using ambient mass spectrometry

We have known about altered metabolism in cancer cells since Otto Warburg described it 97 years ago. But can we take advantage of this knowledge in curing cancer? Jim Higginson explains the value of smoke generated during cancer surgery. The...

Transnasal oesophagoscopy (TNO)-guided secondary tracheoesophageal puncture (TEP) under local anaesthesia

Here, the authors describe a convenient use of the transnasal oesophagoscope to create a new tracheoesophageal puncture in the outpatient clinic setting. Tracheoesophageal puncture (TEP) with voice prosthesis insertion is a reliable and effective technique for surgical voice restoration (SVR)...

Medical racism and the surgical ‘correction’ of the nose in Brazil

Anthropologist Professor Carmen Alvaro Jarrín has conducted extensive research into plastic surgery practice in Brazil. Here, she explains why social and cultural ideas about race may shape rhinoplasty objectives for patients and surgeons in the country. Health professionals worldwide are...

Lipofilling for scar improvement

Since Coleman et al. in 1991 reported on lipofilling, numerous applications have been reported; these include but are not limited to contour restoration, lip augmentation, and wrinkle therapy. There has also been some one off reported improvements in scars following...

Neuromod publishes results of second large-scale clinical trial for tinnitus, shows greater improvement of symptoms

Neuromod Devices, the medical device company specialising in tinnitus, has published the results of its TENT-A2 (Treatment Evaluation of Neuromodulation for Tinnitus – Stage A2) clinical trial in the scientific journal, Nature – Scientific Reports in a paper titled ‘Different bimodal neuromodulation settings reduce tinnitus symptoms in a large randomized trial’.

What’s the risk of regrowth with partial (intracapsular) tonsillectomy

Partial (intracapsular) tonsillectomy is enjoying somewhat of a revival offering the potential for less postoperative pain and bleeding whilst relieving the obstructive element. The authors look at 303 patients, 82 of whom had partial tonsillectomy using coblation. They measured pre...

Lingual tonsils and obstrucive sleep apnoea syndrome (OSAS)

Obstructive sleep apnoea can be due to narrowing of the retrolingual space by hypertrophic lingual tonsils. The authors studied 11 patients (five males and six females with a mean age of 44.3 years and a mean BMI of 28.6). All...

Implications of tonsillectomy in very young children

This is a comprehensive study comprising 157 children who underwent tonsillectomy below the age of two years, mainly for sleep-disordered breathing (86.6%) and recurrent tonsillitis (7%). With relatively recent understanding of OSAS, the indications for tonsillectomy in children under two...

Genetic discovery using animal models: presbyacusis

By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...

The changing landscape for hearing loss therapeutics: novel advances of gene and cell therapies

Recent years have seen advances in hearing loss therapeutics, with novel treatments trialled in humans, and others nearing promising first-in-kind clinical trials. First successful clinical trials for a specific form of genetic hearing loss Very exciting news has emerged in...

Using psychological behaviour change theory in vestibular practice

Fiona Barker explains the importance of recognising and understanding how habitual behaviours in vestibular patients can affect treatment outcomes, and how we as audiologists can support and encourage patients to modify these behaviours and perhaps address our own professional behaviours...

COVID-19 in patients with chronic rhinosinusitis with polyps. Are they at risk?

COVID-19 entry factors are highly present in nasal epithelial cells. These factors include ACE2 and TMPRSS2. Their presence in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) was not investigated before. Authors investigated expression of ACE2 and TMPRSS2 in two...