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Eosinophilic complications during dupilumab therapy
Dupilumab is a humanised monoclonal antibody that targets type 2 inflammation by blocking IL-4 and IL-13 signalling. Reported adverse events from its use include injection site erythema, conjunctivitis, arthralgia and hypereosinophilia. The potential for more severe eosinophilic-related complications such as...Hearing about genes
I have been fortunate in my career to travel as an invited lecturer at many hospitals, universities and professional societies around the world. I have spoken to audiology societies, otolaryngology societies, and university communication disorders programmes in Europe, Asia, Africa,...
Neurological complications associated with managing degenerative cervical myelopathy
Degenerative cervical myelopathy (DCM) is a common neuropathologic status due to degenerative changes to the cervical spine. There are multiple operative techniques available, including anterior cervical discectomy and fusion, anterior cervical corpectomy, laminoplasty, laminectomy and laminectomy with fusion. C5 palsy...
Are elective facelifts a good idea after head and neck cancer radiotherapy?
The aim of this study was to assess the safety of elective cervicofacial rhytidectomy following radiotherapy for head and neck squamous cell carcinomas (HNSCC). A greater proportion of HNSCC patients are infected with certain strains of the human papillomavirus, which...
Safety factors in use of balloon tuboplasty
Various medications used to restore eustachian tube function have unpredictable results and these are often disappointing. Balloon dilatation of eustachian tube came around 2010 but has not really gained momentum, mainly due to apprehended complications. In this review article, the...
Swallow assessment: is clinical judgement or objective measurement more reliable?
Swallowing difficulties are life threatening and are the most common referral reason to speech and language therapists working with the adult population. Video fluoroscopic examination is a common instrumental tool used to assist in the assessment of the risk of...
Safety of outpatient thyroid and parathyroid surgery
This study examined the safety and outcomes of matched groups of patients, undergoing either inpatient thyroid / parathyroid surgery or being discharged within eight hours of surgery. There were 2,362 patients in each group who were matched by a ‘propensity...
Management of traumatic facial palsy
Most traumatic facial palsies resolve with conservative management. Early facial nerve decompression is indicated in acute complete traumatic facial palsies. House–Brackmann (HB) classification is used universally to classify the severity of the facial nerve injury, but few centres have availability...
Diagnostic features of acute invasive fungal sinusitis
Acute invasive fungal sinusitis (AIFS) is a rare but frequently lethal condition, commonly associated with a high morbidity among those that survive. It has gained recent media attention on account of its increased incidence following infection with (and treatment for)...Treating voice disorders in singers
There are few ENT surgeons who have as much insight into singers’ problems as Nick Gibbins. A good knowledge of working patterns, repertoire and the physiology of ‘vocal athletes’ is essential. He shares a few thoughts with us. When deciding...
