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Contemporary UK experience of oropharyngeal transoral laser microsurgery

It is well recognised that the current emergence of HPV-positive oropharyngeal squamous cell carcinoma (OPSCC) as a distinct disease entity requires a fresh look at standard treatment modalities that are based on chemoradiotherapy for stage III/IVa OPSCC. The Newcastle experience...

The hippo and the nose

Chronic rhinosinusitis with nasal polyps (CRSwNP) leads to histological changes including thickening of the basilar membrane and epithelial proliferation. Molecular mechanisms underlying these changes are still not fully clear. A signalling pathway called the hippo with Yes‐associated protein (YAP) as...

Systemic steroids for sensorineural hearing loss

This Japanese retrospective study looked at whether the dosage of prednisolone affects the response rate in patients with idiopathic sudden sensorineural hearing loss. The authors included a total of 159 patients over a 14-year period who were treated with 200mg/day...

Budesonide nasal irrigation for chronic rhinosinusitis: is it effective and safe?

Budesonide respules used in nasal irrigations as part of chronic rhinosinusitis management are usually at a dose of 0.25 mg to 2 mg, which is substantially higher compared to budesonide nasal spray, typically ranging from 64 to 256 micrograms. Hence,...

The effects of polypharmacy in the elderly

Another pill to cure the ill? Alec Lapira discusses the warning signs of polypharmacy in the elderly population. Polypharmacy in the elderly Polypharmacy – defined as the use of five or more medications – occurs in 20–37% of older people...

Mucormycosis: In conversation with Dr Deepak Haldipur and Dr Aditya Moorthy

COVID-19 has ravaged the world in the past 18 months. The second wave in many countries was deadlier than the first. Mucormycosis, infamously labelled ‘the black fungus’ has affected some countries, such as India, in epidemic proportions within this COVID...

Endolymphatic sac surgery: controversial procedure for the treatment of Ménière’s disease

Landmark Paper: Thomsen J, Bretlau P, Tos M, Johnsen NJ. Ménière’s disease: endolymphatic sac decompression compared with sham (placebo) decompression. Ann N Y Acad Sci 1981;374:820-30. Of all of the chapters in the Landmark Papers book, the chapter that discussed...

Targeting the microbiome in chronic rhinosinusitis

Researchers at St Paul’s Sinus Centre and UBC in Vancouver are testing a novel treatment for CRS: transferring mucus from a healthy donor into a patient’s sinuses. Chronic rhinosinusitis (CRS) is one of the most common diseases managed by otolaryngologists...

European funding for the tinnitus research network TINNET

Over 70 million people in Europe experience tinnitus, and for seven million it creates a debilitating condition. Severe tinnitus is often associated with depression, anxiety and insomnia, resulting in an enormous socio-economic impact [1]. It has been estimated that 13...

Patient-centred audiological rehabilitation: facilitating and hindering factors for implementation

Introduction Patient-centred care in the health sector is a worldwide concern [1, 2]. Patient-centred rehabilitation is characterised by availability, appropriateness, preference, and timelines [3]. A consensus report by the Institute of Medicine [4] defines a patient-centred approach as ‘providing care...

In conversation with Helen and De Wet in Paris: cochlear implants in the year 2074

The World Congress of Audiology (WCA), held in Paris, France, in September 2024, provided a fantastic opportunity to reconnect with colleagues from around the globe. I took the chance to sit outside in the sunshine with De Wet Swanepoel from...

In conversation with Helen and De Wet in Paris: cochlear implants in the year 2074

The World Congress of Audiology (WCA), held in Paris, France, in September 2024, provided a fantastic opportunity to reconnect with colleagues from around the globe. I took the chance to sit outside in the sunshine with De Wet Swanepoel from...