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Hearing loss and Alport syndrome

Alport syndrome (AS) includes a group of hereditary diseases caused by mutations in the COL4A3, COL4A4 or COL4A5 genes. These genes are responsible for the biosynthesis of α3, α4 and α5 collagen IV chains, which are located in the glomerular...

The role of artificial intelligence and applications in ENT surgery

AI is progressing apace. If you’re wondering how it might affect our working lives in ENT, read on for insights and a pilot study that show us what may be possible. The recent launch of ChatGPT, an open access artificial...

Precision and personalised genomic and epigenomic medicine in audiology/hearing loss

A detailed look at the pathogenesis of acquired hearing loss due to exposure to ototoxicity during pregnancy or shortly after birth. Insights from genomic medicine have shown that, along with environmental factors causing epigenetic alterations, hearing loss may be caused...

Taking a fresh look at otoacoustic emissions

So what has changed in four decades of OAEs? Do we now have all the answers? Have we reached our optimum recording ability? Professor Kemp explains what we know, what we don’t know and what’s to come. In the 40...

Evidence-based practice: management of sudden sensorineural hearing loss

What is the current evidence for medical management of sudden sensorineural hearing loss? Jessica Choong and Stephen O’Leary present a review of the current evidence of treatments options. Sudden sensorineural hearing loss (SSNHL) causes significant distress and, in many cases,...

In Memoriam: Charles I. Berlin, PhD

Dr Charles “Chuck” Berlin was an international guiding star in hearing research and clinical audiology for over 50 years. He was a renowned scientist, mentor, teacher, clinician, colleague, accomplished musician, and friend to hundreds of colleagues from around the world....

ENT Update 2023 Conference

Hesham Negm, Cairo University, Egypt. In the famous historical city of Muscat, capital of Oman, the two-day ENT Update 2023 Conference was held alongside pre- and post-conference teaching and training courses organised by the ENT Division, Department of Surgery, Sultan...

Supplementing intranasal cortical steroids with montelukast: does it help?

Intranasal steroids are widely used in the treatment of allergic rhinitis. Whether or not the addition of montelukast helps was assessed in this study. This was a single centre prospective randomised double-blind placebo-controlled trial of two groups of patients, one...

Prophylactic gastrostomy tubes in advance of chemoradiotherapy for advanced head and neck malignancies – are they worthwhile?

It is well recognised that radical chemoradiotherapy (CRT) for head and neck cancers can significantly affect swallowing, especially if radiotherapy is delivered to the hypopharynx and/or both sides of the neck. As such, prophylactic gastrostomy tubes are often advocated in...

Subtypes of vestibular migraine

The authors argue that the current Barany criteria (ICVD) for vestibular migraine (definite and probable – dVM and pVM) are too restrictive. For instance, whereas a category of chronic migraine with or without aura is recognised in ICHD-3, ‘chronic VM’...

From Hippocrates to COVID-19: sniffing out the disease

The ancient Greek physician, Hippocrates, used the ‘art of smell’ to diagnose diseases around 400BC. He also formulated miasmatic theory, which posited that disease is caused by bad smells. Bad air was strongly believed by many physicians to be the...

EVOTION: Big data supporting public health policies for hearing loss

Big Data? Biosensors, smart hearing aids and smartphones? The EVOTION Project has it all and more! What will this project tell us about the future of hearing management? Doris-Eva Bamiou, Giorgos Dritsakis and Louisa Murdin, members of the EVOTION team,...