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Immunosuppresants and ototoxicity

There is a wide range of immunosuppressant drugs ranging from calcineurin inhibitors (e.g. cyclosporine), anti-folic agents (e.g. methotrexate) to anti-TNF and monoclonal antibodies, many of which could be ototoxic. The authors performed a systematic review assessing ototoxicity secondary to immunosuppressant...

Pulsatile tinnitus, one more piece in the jigsaw

Pulsatile tinnitus (PT) is a common ENT symptom. It can generally be divided into venous and arterial. Arterial PT might be investigated with a CT scan while a venous one with an MRI or an MRV (MRI Venogram). Anecdotally, arachnoid...

Diagnostic features of acute invasive fungal sinusitis

Acute invasive fungal sinusitis (AIFS) is a rare but frequently lethal condition, commonly associated with a high morbidity among those that survive. It has gained recent media attention on account of its increased incidence following infection with (and treatment for)...

Active surveillance for papillary thyroid cancers – what is the risk of progression?

Papillary thyroid cancers (PTCs) are generally considered to be indolent malignancies with favourable outcomes. Active surveillance (AS) has consequently been trialled as a management option for small PTCs with no evidence of regional lymph node involvement, especially papillary thyroid microcarcinomas...

Is Gamma Knife Surgery effective for intracanalicular vestibular schwannomas?

Vestibular schwannomas (VSs) are rare, occurring in approximately five per 100,000 adults a year. In circa 8% of cases, the VS is contained within the internal auditory canal, i.e. intracanalicular (iVS). Although radiosurgery is a recognised treatment modality for VSs,...

Introduction to Sound: Acoustics for the Hearing and Speech Sciences

The fifth edition of Charles E Speaks’ Introduction to Sound Acoustics for the Hearing and Speech Sciences is a comprehensive, teaching-first textbook spanning 11 chapters. It begins with the nature of soundwaves presented in concise, well-structured sections on transmitting mediums,...

An otological cure for globus?

Globus pharyngeus is a common benign condition frequently encountered in ENT practice. Laryngopharyngeal reflux and psychological stressors are often considered to be contributory factors, but globus symptoms do not always respond to antacid medications. Such medications can also be limited...

Publishing - a predictor of an academic career in ENT?

Achieving a publication as a medical student renders ENT trainees six times more likely to publish again during postgraduate surgical training. But how does this correlate with subsequent subspecialty fellowship training and a career in academia? Johnson et al examined...