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Bell’s palsy incidence in Korean population

Bell’s palsy is an acute idiopathic paresis or paralysis of the peripheral facial nerve. It is the most common cause of facial nerve palsy with a reported incidence ranging from 11.5–55.3 per 100,000. The aetiology remains unclear. Several studies have...

Role of ultrasonography-guided fine-needle aspiration in management of the neck after chemoradiotherapy

Primary chemoradiotherapy (CRT) is a well-established treatment for locally advanced head and neck squamous cell carcinoma (HNSCC). However, not every patient has a complete response to this treatment modality, necessitating eventual salvage neck dissection. Some patients with persistent adenopathy following...

T1 lip cancer and cervical lymph node metastases

The management of large lip squamous cell carcinoma (SCC) (T2, T3, T4 tumours) or those with nodal disease is well established. However the management of T1N0 tumours is controversial due to the assumed low risk of occult lymph node metastases....

New aminoglycosides with reduced ototoxicity risk

Aminoglycoside antibiotics are widely used for infections affecting patients of all ages and at different sites, however they carry a risk of ototoxicity, nephrotoxicity and rarely peripheral neuropathy. Preventing ototoxicity is crucial to the maintenance of auditory function and quality...

The ‘My Hearing Explained’ tool: audiologist and client perceptions

The study notes that the pure tone audiogram has been the primary clinical and counselling tool used by clinicians to assess and describe hearing thresholds to individuals and families since 1922. The Ida Institutes, ‘My Hearing Explained’ tool has become...

Olfactory ensheathing cells and their safe harvest

This interesting and unique paper not only demonstrates that biopsy of olfactory mucosa in the region of the superior turbinate is a safe procedure but also provides valuable insight into an engaging area of research by a world class team...

Organoids in otolaryngology

This interesting review article summarises the status as well as future prospects of organoid technology in our field. Organoids are a mass of cells which are typically cultured in vitro with 3D technology. They simulate miniature tissues and organs and...

Patron saints of the ear

We all know that ear symptoms include hearing loss, vertigo, tinnitus and otalgia, but did you know there are patron saints for all these symptoms? John Riddington Young shares an overview of the patron saints of the ear, inspired by...

Metformin, the magical solution!

Both noise-induced hearing loss (NIHL) and vestibular schwannomas (VSs) pose a challenge in terms of management. Metformin was suggested as a potential therapeutic drug for NIHL when the drug-target interaction data was investigated. Additionally, there are studies which demonstrate reduction...

The structure and function of DNA

DNA structure and replication Genetic information within multicellular organisms, including man, is stored in molecules of deoxyribonucleic acid (DNA), which reside within the chromosomes of each cell nucleus. A DNA molecule consists of two very long chains, or strands, of...

Head and neck cancer and PET-CT

Positron emission tomography-computed tomography (PET-CT) is an imaging technique in which abnormalities of tissue metabolism are precisely superimposed onto the anatomy. It relies on the premise that malignant cells are more metabolically active compared with non-malignant cells. On this basis,...

From patient to performer

Peter Cawrey lives in Harpenden, Hertfordshire, with his wife Dorothy. He had a salvage laryngectomy for squamous cell carcinoma in 2015, three years following his initial radiotherapy. Due to complications and a complex recovery, he has elected not to have...