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Case study suggesting mtDNA mutation as a tinnitus factor: ND1:m.3394T>C

Konadath et al report a genetic case study of a 24-year-old female experiencing reduced hearing sensitivity and tinnitus along with a blocked sensation in her right ear, sudden onset one year prior with no other otological complaints. Standard audiometry along...

Recruitment of Sudden Hearing Loss Patients for Clinical Trial: Novel Compound AC102 Outperforms Corticosteroids Preclinically

While corticosteroids are widely used to treat Sudden Sensorineural Hearing Loss (SSNHL), there is still no therapy with proven efficacy and regulatory approval for this debilitating condition.

OTO-104 in noise-induced and cisplatin-induced hearing loss

These two animal studies report on potential new applications for intra-tympanic OTO-104, a slow-release hydrogel formulation of dexamethasone that is currently being used in a Europe-wide randomised trial for Ménière’s disease. In the first paper, guinea pigs were given a...

Cochlear implantation in SSD

There are currently several trials for cochlear implantation (CI) in single-sided deafness (SSD) being undertaken to answer some of the questions this paper from New York raises. Who is best suited to receive one? What are their outcomes and how...

Chemo-radiation in elderly patients with head and neck cancers

Chemo-radiotherapy is the standard of care for organ preservation in stage three and four oropharyngeal cancer, prospective data on patients over 65 has not been available as they are usually excluded from randomised trials. This paper reviews the experience of...

Is it really working? Assessment versus real-life language measures

Research in the field of language treatment and rehabilitation to date has used single-word naming as a controlled measure of outcome. Yet, given people do not actually communicate in single words, there is much debate as to whether this approach...

Management of single-sided deafness in adults: a bone conduction solution

Single-sided deafness (SSD) presents a limited number of methods for management, and not all of them meet the patient’s expectations. The aim of this article is to set out the available bone-conduction treatment methods for managing single‑sided deafness in adults....

Quick & Efficient Procedures with DTR’s Sterile Single-use Aural Care Range of Instruments

DTR Medical’s Single-use Aural Care Instruments have been carefully designed to assist in the restoration of hearing through a Hearing Aid when the mechanism becomes sclerosed or fused together.

2nd UEP/BLA Joint Meeting

After the success of last year’s inaugural joint meeting in London between the British Laryngological Association (BLA) and the Union of the European Phoniatricians (UEP), the two bodies are coming together again in the charming city of Zagreb, the capital...

AOT Annual Conference 2026

Register and submit abstracts: Conference registration: https://tinyurl.com/4p9nwej6 Abstract submission: https://tinyurl.com/3buz4da9

From the editor...MayJun19

Declan Costello, MA, MBBS, FRCS(ORL-HNS),Editor, ENT & Audiology News;Consultant Ear, Nose and Throat Surgeon, Wexham Park Hospital, Slough, Berkshire, UK. E: d.costello@nhs.net Welcome There are few people in the specialty of ENT whose names become truly global, but Heinz Stammberger,...

Back to the Future

Normally my objective for this column is to highlight an innovation that is already fully realised and on the market. Sometimes it can be fun instead to look forward to what innovations are coming down the pipeline. With that in...