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Allergic rhinitis, the usual suspects
Allergic rhinitis (AR) is characterised by allergen binding to IgE on mast cells and basophils and subsequent histamine, prostaglandine D2 (PGD2) and cysteinyl leukotrienes (cysLTs) release causing early-phase response. This is followed by late-phase response mediated by eosinophils. Other cells,...
Tablet-audiometer school hearing screening in the context of a developing country
This paper presents a novel use of innovation to tackle the challenges of providing school-age hearing screening in low and middle income countries (in this case Nicaragua, second poorest in the western hemisphere), from the creators of a tablet-based audiometer...
The association between pregnancy and otosclerosis could be due to psychosocial factors around parenthood rather than biological factors
The association between pregnancy and otosclerosis is controversial. If pregnancy physiologically increases the likelihood of otosclerosis progression, then one would expect that there would be a difference between male and female patients with regards to whether having children affects how...
Olfactory disorders in COVID-19
This Turkish prospective longitudinal observational study evaluated olfactory disorders (OD) and recovery processes in patients with COVID-19 infection at three time points within the first month of diagnosis: time of diagnosis with positive PCR test; time of first negative PCR...Hearing loss and cognition: something to think about
Irace, Chern and Golub propose causal and non-causal mechanisms for the links between hearing loss and dementia, concluding with a discussion of several proactive measures available to help preserve neurocognitive health in older adults with hearing loss. What is age-related...
Treatment of internal carotid artery blowout with embolisation and bypass grafting (nasopharyngeal carcinoma)
Carotid artery blowout syndrome (CBS) occurs when there is rupture of the carotid artery causing massive epistaxis and bleeding through the oral cavity caused by tumour invasion, surgery, radiotherapy, or infection. This article proposes a revascularisation strategy for internal carotid...Multi-channel cochlear implants: past, present and future
Forty years since the first multi-channel devices were implanted, who better than Ingeborg Hochmair, who has been a key figure throughout their evolution, to offer her thoughts on the past, present and future of multi-channel cochlear implants? Read on for...
Foretelling: post-stroke recovery of dysphagia is predicted by cognition
Around two thirds of people in the acute phase of stroke recovery will experience dysphagia. Up to six months following a stroke this may be present in 13-18% of cases. The degree of cognitive impairment seems to be associated with...
