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New aminoglycosides with reduced ototoxicity risk

Aminoglycoside antibiotics are widely used for infections affecting patients of all ages and at different sites, however they carry a risk of ototoxicity, nephrotoxicity and rarely peripheral neuropathy. Preventing ototoxicity is crucial to the maintenance of auditory function and quality...

Preoperative tumour embolisation

This review article analyses the role of preoperative endovascular tumour embolisation in the treatment of a variety of hypervascular head and neck lesions including juvenile nasal angiofibroma, glomus tumour, carotid body tumours, and meningioma. Although the concept of tumour embolisation...

Resection margins in head and neck surgery

Although an increasing proportion of head and neck malignancies are treated with non-surgical modalities, when surgery is undertaken an incomplete clearance results in significantly worse prognosis. However, the intraoperative assessment of an adequate margin is difficult. The personal practice of...

Work and the risk and carcinoma of the larynx

This is a census on the national cancer registry in France to detect professions at a higher risk of squamous cell carcinoma of the larynx. During the period 2001-2016 there were 244 registered cases of cancer of the larynx. Amongst...

Death related to epistaxis

One of the commonest emergencies presenting in ENT is epistaxis. The presentation can be through accident and emergency or through ward referrals. In this national audit of epistaxis management involving 113 centres, it was noted that 33 of the 985...

Is there evidence to support early discharge of patients with tonsillitis, quinsy and epistaxis?

The COVID-19 pandemic, with its unprecedented pressures on the NHS, demands changes in the management of common ENT emergencies. In this review article, information has been gleaned from 22 relevant articles on how this can be done. The Portsmouth tonsillitis...

How can we treat a patient with aural fullness?

Aural fullness is a common complaint that we often come across in many of our otology patients. Management of this condition can be quite challenging. Common differentials include eustachian tube dysfunction, patulous eustachian tube dysfunction, otitic barotrauma, superior canal dehiscence...

COOL therapy for cisplatin-induced hearing loss

Cisplatin is a commonly used cancer therapy, with nearly 50% of patients undergoing chemotherapy receiving cisplatin as part of their regimen [1]. Depending on the dose, incidence of hearing loss has been reported as 12-100% in adults, and 37-94% in...

Machine learning and the future of otolaryngology

If you are over 30 years of age, you have witnessed a technology revolution that has grossly affected how we live: computers have come from being an oddity to an everyday feature in our households and places of work; the...

Head and neck robotic surgery – considerations for the surgical trainee

In 2021, training in head and neck cancer surgery would be incomplete without some robotic resections under the belt. Henry Zhang explains how he did it and outlines the options available. With a wide range of applications in both benign...

Embracing deafness and the silent world

Brian Kokoruwe shares his journey from growing up during civil war in Nigeria to becoming Director of Deaf UK Athletics and a published author. While I am active in the Deaf BSL community, involved in Deaf sports and the Government...

The curse of Sports Illustrated

“Not a supernatural curse, but a basic statistical concept of blinding simplicity.” What is ‘regression to the mean’? I am reliably informed that our former North American colonies publish a periodical known as Sports Illustrated (note, incidentally, the characteristically incorrect...