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Patients with severe uncontrolled CRSwNP respond to biologics in the real world

Clinical trials have demonstrated that biologics are effective in treating patients with chronic rhinosinusitis with nasal polyps (CRSwNP). This multicentre (15 tertiary care centres in France) observational prospective cohort study aims to examine the effectiveness of biologics in treating CRSwNP...

Extranodal extension following surgical resection of HPV-positive oropharyngeal cancer – is adjuvant radiotherapy alone sufficient?

Human papillomavirus (HPV) is a known aetiological factor in oropharyngeal squamous cell carcinoma (OPSCC). HPV-positive OPSCC is recognised to have a more favourable prognosis than HPV-negative disease. Treatment deintensification for HPV+ OPSCC has therefore been an area of research focus...

EBM Stats Calc: there’s a stat for that

Quantifying the value of a specific test or intervention for a patient is no easy feat. Even when the value of a given test or intervention has been established, there may be additional case-specific factors to consider that are not...

The National Bone Conducting Hearing Implant Registry

Are you an otologist with an interest in implant surgery? Is your unit on the registry? If not, you’d better have a good excuse after reading this… What is the National BCHI Registry? The National Bone Conducting Hearing Implant (BCHI)...

Why screen for hearing loss in adults?

Introduction Hearing loss affects over 10 million people in the UK – one in six of the population. Of over 50-year-olds 41.7% are estimated to have some form of hearing loss. This rises to 71.1% of over 70-year-olds, over half...

The central ENT decontamination model: a help or a hindrance?

According to NHS England, over 400,000 patients were waiting for ENT treatment in the UK in January 2022. This figure forms part of the overall 33.5% increase in the number of patients waiting for Referral to Treatment (RTT) compared to February 2020[1].

The future of facial plastics and rhinoplasty

Interest in facial plastic surgery and in particular rhinoplasty has never been greater. From his wealth of experience in the field, Professor Palma outlines the potential problems of this increasing popularity and how they may be addressed, areas on which...

Adolescence, drug use and body image

Teenagers are notoriously conscious of how they are perceived by others. Dr Saraiva and colleagues explain how this can lead to problems with substance abuse for both boys and girls, and discuss the different substances they may encounter. Adolescence is...

In conversation with John Carlisle: the silent hero shaping medical publication integrity

Have you ever been curious as to what your anaesthetist is getting up to on their laptop during long cases? Me neither, but I always generally assumed they were trading Bitcoin, solving the Riemann hypothesis and buffing their Tinder profile....

The role of prediction and gain in tinnitus

Dr Will Sedley is a Clinical Academic Neurologist who has done groundbreaking work in the field of tinnitus mechanisms. Here, he introduces and explains the concepts of prediction and of gain as they relate to troublesome tinnitus. This article focuses...

In conversation with John Carlisle: the silent hero shaping medical publication integrity

Have you ever been curious as to what your anaesthetist is getting up to on their laptop during long cases? Me neither, but I always generally assumed they were trading Bitcoin, solving the Riemann hypothesis and buffing their Tinder profile....

In conversation with Professor Charles Liberman

Just before I left Cambridge to work with the Hearing Sciences group in Nottingham, I spent a very happy hour alone in the company of Professor Charles Liberman, the Director of the Eaton-Peabody Laboratories based at the Massachusetts Eye and...