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What causes delays in head and neck cancer treatment?
This article identifies which factors are responsible for delays in cancer management by a retrospective case-control series study, statistically comparing two groups, each of 50 patients, one receiving timely treatment and the other breaching set targets. It was observed that...
Interleukins, cilia and polyps
Interleukins (ILs) including IL13 (Th2 cytokine) are inflammatory mediators and their role in asthma has been detailed before. This study explores IL13 receptor expression in chronic rhinosinusitis with nasal polyps (CRSwNP). The authors investigate protein and mRNA expression levels of...Digital otoscopy with AI diagnostic support: making diagnosis of ear disease more accessible
Following Carolina Leal’s interview with Prof De Wet Swanepoel on the HearScope system, Spotlight on Innovation asked Dr Jenny Nesgaard Pedersen to review the new AI feature in HearScope system’s capabilities. In the last decade, artificial intelligence (AI) and machine...
Prevention is Better than Cure: Learning from Adverse Events in Healthcare
Ian Leistikow has an impressive CV; as Senior Inspector at the Dutch Healthcare Inspectorate and a member of the Strategic Advisory Board of the International Forum on Quality and Safety in Healthcare, it is clear he is passionate about advancing...
SoundPrint: an app for finding quieter restaurants
"Is there any chance the music could be turned down a bit”, I asked our server politely on a rare evening out with my husband. We had spent the previous half-hour shouting at each other, only to have the other...
When should we decompress the facial nerve in Bell’s Palsy?
It has been over three decades since Fisch popularised facial nerve (FN) decompression for Bell’s Palsy. Studies further exploring this have been few since, partly due to the major complications that can occur following this type of surgery. The current...
Application of paper patching in patulous eustachian tube
The condition of patulous eustachian tube, as opposed to dysfunctional eustachian tube, is less frequently diagnosed. Symptoms related to this, such as autophony, aural fullness, ‘being under water’, ‘hearing their own breathing’, and hearing sensitivity (varying in either direction) can...
Prioritisation of surgery for pituitary tumours
This study is based on the findings of internationally renowned skull base surgeons who convened to recommend this stratification scheme. The study authors report that incidental diagnosis of pituitary tumours during routine imaging as well as early identification of visual...
Short-term risk of falling after cochlear implantation
This paper examined the effect of cochlear implantation on balance function in 16 adult patients. The authors assessed balance pre- and (two weeks) post-operatively by timing how long each patient was able to stand on a foam pad with their...Harnessing head and neck cancer genomics for personalised medicine
Luc Morris updates us on the future of cancer diagnosis and treatment, which lies in “personalised oncology”, where specific molecular alterations of each tumour will be identified, and matched with actionable alterations in existing therapies, ushering in the era of...
A mouth-rinse test that can screen for oral cancer?
This paper presents a promising screening tool for oral cancer – using a simple chlorhexidine mouth-rinse. The hypermethylated ZNF582 and PAX1 markers were chosen based on previous studies using oral scraping methods of collection and have been shown to be...
