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Current perspectives of tinnitus and its management

Whilst there are various therapeutic options for ameliorating the impact of tinnitus, there is no current approved treatment for attempting to eradicate, or even for reducing, the loudness of tinnitus.

Is Dymista® useful for paediatric allergic rhinitis?

Allergic rhinitis (AR) affects up to 14.6% of the paediatric population. Whilst a recent Cochrane review has considered the evidence for intranasal corticosteroids as `weak and unreliable’ in paediatric AR, this product is a novel formulation combining Fluticasone and Azelastine...

Metformin, the magical solution!

Both noise-induced hearing loss (NIHL) and vestibular schwannomas (VSs) pose a challenge in terms of management. Metformin was suggested as a potential therapeutic drug for NIHL when the drug-target interaction data was investigated. Additionally, there are studies which demonstrate reduction...

Landmark clinical trial into treatment for severe hearing loss launches

Researchers at the NIHR Nottingham Biomedical Research Centre and the University of Nottingham are launching a new study, sponsored by the University of Nottingham, which will inform the most effective treatment for people with severe hearing loss globally (those with...

Will it ever happen?

Audiology is a rapidly evolving field, with many exciting developments on the horizon. David Baguley identified some topics of interest, and asked some international experts ‘will it ever happen?’ Gene therapy for deafness After years of development, gene therapy for...

Hearing Aid Dispensing Training Manual

The Hearing Aid Dispensing Training Manual is primarily designed to support those sitting their State Hearing Aid Dispensing practical exams in the US. The book is easy to read, comprehensive and logical in its approach to supporting those sitting their...

Poor allergic rhinitis control increases the overall costs

Allergic rhinitis and asthma are common and can have significant effects on quality of life. However, not many studies have focused on the economic effects. The authors of this study performed a large-scale (over 60,000 patients) observational study to analyse...

Should intratympanic steroids be the first line treatment for sudden sensorineural hearing loss?

This article looked at whether intratympanic steroids (ITS) provide more benefits over systemic steroid therapy (SST) as initial therapy in patients with idiopathic sudden sensorineural hearing loss (ISSHL). This meta-analysis study, based on published RCTs, concluded that ITS treatment exhibited...

Antiseptics to combat otorrhea in the era of antibiotic resistance

This nice scientific paper pits various antiseptic solutions against each other to determine which has the most bactericidal properties. Five different antiseptics were applied to MRSA and quinolone-resistant pseudomonas species, which are both difficult to treat with conventional ototoxic medications....

The Impact of sleep endoscopy for paediatric obstructive sleep-disordered breathing

Paediatric obstructive sleep apnoea (OSA) is not always resolved or improved with adenotonsillectomy. Persistent or complex cases of paediatric OSA may be due to sites of obstruction in the airway other than the tonsils and adenoids. Investigation of paediatric obstructive...

Paediatric pain control post-tonsillectomy

The use of codeine in the paediatric population is widely debated since the American Food and Drug Administration (FDA) published warnings regarding overdose and death following the usage of codeine. Codeine is metabolised by the polymorphic cytochrome PY4502D6 (CYP2D6) in...

Genetics of IP-III

The authors provide a literature review of the genetic basis and clinical features of incomplete partition (IP)-type III. The condition is seen typically in males and is due to mutation in the POU class 3 homeobox 4 (POU3F4) gene which...