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Active smoking predicts poor outcome in HPV positive oropharyngeal squamous cell carcinoma
Tobacco smoking is a well-known risk factor in human papilloma virus (HPV)-negative head and neck squamous cell cancer. Its effects include increased risk of treatment failure, distant metastases and reduced overall survival. HPV has been increasingly implicated as a causative...
Thyroidectomy patient survey regarding voice outcomes
One of the common adverse effects following thyroid surgery is a change in voice, which may be related to iatrogenic injury to the recurrent laryngeal nerve or superior laryngeal nerve during surgery or by direct cancer involvement. The burden of...
Predicting the need for salvage laryngectomy
The treatment of laryngeal cancer has seen a shift towards organ preservation strategies with non-surgical treatment offering equivalent survival outcomes. Nonetheless, salvage total laryngectomy (SLT) remains an important curative management option in cases of treatment failure or recurrence. The authors...Unanswered questions in adult ototoxicity associated with platinum-based chemotherapy
Do the potential side-effects on hearing and tinnitus need to be a ‘necessary evil’ of platinum-based chemotherapy? How strong is our evidence base when offering advice to patients and fellow clinicians? David Baguley and his team from the University of...
Adjuvant radiotherapy for locally advanced (T3–4) major salivary gland cancer – survival benefits quantified
Complete surgical excision of major salivary gland cancers (MSGCs) is the current mainstay of curative treatment for this disease. Indications for postoperative radiotherapy according to current UK national guidelines include high-grade tumours, advanced-stage (stage 3–4) tumours, involved resection margins, perineural...Returning to practice
Here, we provide a combination of written guidelines, podcasts and videos providing information on returning to practice and elective services during the COVID-19 pandemic. Resources will be updated as and when they become available. - Guidelines - 7 July -...
Laryngeal Manifestations of Systemic Diseases
Laryngeal Manifestations of Systemic Diseases is a unique reference manual which will cater to a wide potential audience. It would represent a good text for laryngologists coming across patients with known comorbidities or as new diagnoses of underlying pathologies, but...
