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PPPD - the problem with the label
The recently described diagnostic entity of persistent postural perceptual dizziness (PPPD) has its merits regarding guiding intervention and treatment, but the label itself can be problematic for patients. This study was designed to determine the views of patients of the...
Which factors affect the postoperative CSF leak following endoscopic skull base surgery?
Endoscopic skull base surgery is being increasingly performed worldwide for skull base tumours. Common indications include pituitary tumours, rathke cleft cysts, chordomas, craniopharyngiomas and olfactory neuroblastomas. The most common and important complication following endoscopic skull base surgery is postoperative CSF...
Laryngeal disorders associated with HIV infection
Following the introduction, and now widespread availability, of combined antiretroviral therapy, HIV has become a chronic disease with minimal or indeed no negative impact on life expectancy. As a result, there is a growing public health interest in establishing the...
Gastrostomy tube dependence following TORS
Transoral robotic surgery (TORS) for oropharyngeal squamous cell carcinoma (OPSCC) is now a well-established treatment modality for early (T1-T2) disease. Accumulating evidence suggests that one of its main benefits relative to conventional chemoradiotherapy is superior long-term functional outcome, especially with...
Is endoscopic stapes surgery safe and are outcomes comparable to microscopic stapes surgery
Endoscopic techniques for visualisation of the middle ear were described in 1967 by Mer and colleagues, and the use of transcanal endoscopic ear surgery (TEES) has since expanded to a wider range of otologic applications including tympanoplasty and excision of...
How reliable are PTH levels for the prediction of hypocalcaemia after thyroid surgery?
Hypoparathyroidism is one of the most common complications of thyroid surgery. There is significant controversy in calcium management practices post thyroid surgery. The drop in PTH levels has been used to predict the likelihood of hypocalcaemia after thyroid surgery. But...
Does the appearance, texture, and flavour of food affect how we swallow?
Texture modification and the use of thickened fluids are well-known strategies used to facilitate swallowing in people with dysphagia. However, some controversy exists around thickeners and their possible negative impact on hydration and medication absorption. This paper considers other properties...
I saw it on the internet: gathering evidence for clinical decision making
Evidence-based practice is often described as the integration of three sources of information to inform clinical practice, namely: 1) research evidence/practice guidelines; 2) client preferences/needs, and: 3) clinical experience. Speech and language therapists have reported a lack of time and...
A time-saving method for faster cancer diagnosis and treatment
One of the main impediments in achieving UK Government cancer diagnosis and treatment targets is lack of diagnostic capacity. An increase in head and neck cancers by 50% in the last five years has put on additional strain. In this...
Is Gamma Knife Surgery effective for intracanalicular vestibular schwannomas?
Vestibular schwannomas (VSs) are rare, occurring in approximately five per 100,000 adults a year. In circa 8% of cases, the VS is contained within the internal auditory canal, i.e. intracanalicular (iVS). Although radiosurgery is a recognised treatment modality for VSs,...
A systematic review of adjunctive probiotic therapy in the management of chronic rhinosinusitis
It is generally understood that administering substances containing live microbiologically active micro-organisms (probiotics) enhances the treatment of chronic rhinosinusitis. Probiotics manipulate and rebalance the alterations occurring in the local microbiome in chronic rhinosinusitis patients. This results in propagation of healthy...
