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Measuring radiation fibrosis in patients with head and neck cancer

People treated with radiotherapy for head and neck cancer experience several acute and chronic effects of this treatment, of which fibrosis is perhaps the most common. Fibrosis occurs as a wound healing response and leads to scarring and reduced range...

A surgeon’s perspective on the challenges facing cochlear implantation in children

Cochlear implantation in children offers a different set of challenges and goals to adult practice. In this article, Iain Bruce, Professor of Paediatric Otolaryngology in Manchester, UK, explains some of the current clinical and research challenges in paediatric cochlear implantation,...

Trainee-led collaborative research and audit in ENT: where are we now?

In late 2015 INTEGRATE, the UK ENT Trainee Research Network, was formed. Since then, two national projects have been completed and INTEGRATE has grown into a larger, more structured organisation, with otology, head and neck and rhinology subcommittees working alongside...

Cognitive development in children with cochlear implants

This systematic review investigates the comparative cognitive outcomes in children using bilateral versus unilateral cochlear implants, as well as those using cochlear implants versus hearing aids. The review synthesises findings from 30 studies involving a total of 11,986 children and...

Eosinophilic complications during dupilumab therapy

Dupilumab is a humanised monoclonal antibody that targets type 2 inflammation by blocking IL-4 and IL-13 signalling. Reported adverse events from its use include injection site erythema, conjunctivitis, arthralgia and hypereosinophilia. The potential for more severe eosinophilic-related complications such as...

The importance of s-ABR in auditory disorders

S-ABR is a method of recording speech-evoked-potentials, but where does it fit in the clinical and research test battery? Here, the authors examine the opportunities for s-ABR. The integrity of the neural transmission of acoustic stimuli is evaluated by auditory...

Communicating with patients in 
‘Plain English’

Physicians have long been accused of using unnecessarily complicated language and impenetrable jargon as a way of maintaining their status, prestige and high earnings-potential, bamboozling the public and excluding them from meaningful discussion as part of what George Bernard Shaw...

Use of automated audiometry for faster patient access to audiology services?

Manual audiometry has long been the gold standard for establishing hearing thresholds. In recent years, a number of automated audiometry applications have reached the market. In this article, a team from Ireland have put a version of automated audiometry to...

Public Health Planning for Hearing Impairment (2022)

The World Report on Hearing, published in 2021 by the WHO reports that 430 million people in the world have moderate or worse hearing loss, all of whom require rehabilitation [1]. Over 1.5 billion have any degree of hearing loss....

Cancer genetics and signalling pathways in ENT – a review and discussion of how this can be applied to rare tumours

Introduction Cancer cases continue to increase worldwide, and­­ head and neck cancer is a major global health issue, with an estimated global burden of over 630,000 new cases and over 350,000 deaths per year [1]. The term ‘head and neck...

Endoscopic ear surgery in children

The benefits of endoscopes in otologic surgery, which have become increasingly widely appreciated in recent years, are very well suited to the management of paediatric middle ear disease. Although one might imagine that the smaller ear canal of a child...

In conversation with Shelly Chadha 2019

Shelly Chadha works at the World Health Organisation as the Medical Officer for ear and hearing care. Here, Alex Griffiths-Brown interviews her to find out more about her career, challenges she’s faced and her ambitions for the future. Shelly Chadha....