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1086 results found

Prognostic value of neutrophil-to-lymphocyte ratio in HPV-positive oropharyngeal cancer

The authors propose that high neutrophil-to-lymphocyte ratio (NLR) is associated with poor disease-free survival (DFS) in patients with human papillomavirus positive (HPV+) oropharyngeal cancer (OPC). This is a retrospective study that compared the outcomes of 43 patients treated for HPV+...

Reduction in recurrent cholesteatoma rates with bony obliteration tympanoplasty technique

This large retrospective study from the Erasmus Medical Centre in Rotterdam compares outcomes in traditional canal wall up (CWU) and canal wall down (CWD +/- partial obliteration of mastoid bowl) mastoid surgery for cholesteatoma with bony obliteration tympanoplasty (BOT, which...

Blood-sampling prognostic predictors for Bell’s palsy

Bell’s palsy is generally defined as an acute-onset unilateral idiopathic mononeuropathy in the facial nerve. It is of unknown aetiology, however, inflammation is considered a major cause. Electroneurography assessing nerve excitability is the most reliable examination for predicting prognosis of...

Genetics WG4. Improving diagnosis and drug development through the genetic understanding of tinnitus subtypes: a TINNET endeavour

Christopher R Cederroth and Jose Antonio Lopez-Escamez explain how progress is being made to investigate the contribution of genetic factors to tinnitus, including a subtype of ‘extreme’ tinnitus in Ménière’s disease. Genetics WG4 is working towards determining the genetic basis...

Making audiology work during COVID-19 and beyond

‘New normal’ is another phrase that has become synonymous with this pandemic. In this article, consideration for ‘low-touch’ and ‘no touch’ audiological pathways are described for adoption as the ‘new normal’ for hearing healthcare. The COVID-19 crisis has ushered in...

Management of stage IV pharyngolaryngeal lesions

This is a retrospective study of 63 patients presenting with stage four laryngeal and/or hypopharyngeal squamous cell carcinoma. The aim was to define the factors influencing the oncological and functional outcomes of the patients. All patients had T4 lesions with...

Can telemetry predict sleep apnoea in Pierre Robin sequence?

The aim of this study was to see if telemetry data gathered on patients with Pierre Robin sequence (PRS) correlated with sleep study data. A retrospective review of 46 patients from a tertiary referral centre were included in the study....

Does endoscopic tympanoplasty give better results than a conventional approach?

This is a retrospective review looking at two groups of patients who had undergone middle ear surgery for chronic otitis media (perforation, retraction pocket/cholesteatoma) either open or endoscopic. Four hundred and five patients underwent open ear surgery and 501 endoscopic,...

‘Close’ surgical margin in oral tongue redefined, 2.3mm is as good as 5mm

Gold standard treatment of squamous cell carcinoma (SCC) of the oral tongue remains surgical resection of the primary tumour with negative margins. The primary goal is the complete excision of the tumour with no residual cancer cells left behind. A...

Inferior alveolar nerve recovery after ORIF fractured mandible

Mandibular fractures are quite common facial injuries, but aetiology varies with country and age. Common treatment options are open reduction and internal fixation via an intra-oral or extra-oral incision. Nerve injury or dysfunction is often seen preoperatively and may also...

Rates of tonsillitis increase as rates of tonsillectomy reduce

This retrospective study sought to determine the effect of reduced rates of tonsillectomy in England and Wales, over a 13-year period, on rate of hospital admissions for the complications of acute tonsil infection (acute tonsillitis and quinsy), and hospital bed-day...

What blood tests should be requested to investigate vocal cord paralysis?

Patients who are discovered to have a vocal cord palsy with no obvious cause on history or examination routinely undergo investigations to exclude an underlying pathology. Cross-sectional imaging of the relevant recurrent laryngeal nerve is required, but considerable variability has...