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Laryngeal oedema as a side-effect of tyrosine kinase inhibitor therapy

Tyrosine kinase inhibitors (TKIs) such as Imatinib are increasingly being used to treat haematological and solid malignancies. These agents have revolutionised the treatment of chronic myeloid leukaemia in particular. Although better tolerated than most conventional chemotherapy drugs, multiple side-effects have...

Predicting life-threatening complications in deep neck space infections

Deep neck space infections, arising usually from tonsils and lymph nodes in children and dental source and salivary glands in adults can be life threatening. It is therefore important to recognise the variables which indicate immediate intervention to prevent fatalities....

New biomarkers for salivary gland tumours

Salivary gland tumours comprise approximately 6-8% of head and neck neoplasms. Elevated haematological inflammatory markers, such as neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR), have been shown to be predictive and prognostic in various malignancies. This...

Antioxidants for bacterial rhinosinusitis

This Turkish laboratory animal-based study looked at the effects of alpha-lipoic acid on inflammation, oxidative status, and tissue integrity in an animal model of experimentally induced acute rhinosinusitis and to compare these effects with antibiotic treatment using cephalosporins. Alpha-lipoic acid...

59th Inner Ear Biology Workshop (IEB 2024) and 7th International Conference on Hyperacusis and Misophonia (ICHM7)

This September, two scientific meetings were held together in Warsaw, Poland: the 59th Inner Ear Biology Workshop and the 7th International Conference on Hyperacusis and Misophonia.

Sustainability guidelines to reduce single-use items in ENT outpatients

ENT surgery generates significant waste, with single-use instruments and packaging as key contributors. This article outlines recommendations on sustainable practice that can be adopted into ENT departments. Climate change is one of the greatest threats to human health in the...

Imaging in hyperparathyroidism

Following their caudal migration at eight weeks of development, the parathyroid glands normally locate posterolaterally to the upper pole of the thyroid gland at the level of the cricoid cartilage (superior parathyroid glands arising from the fourth branchial pouch and...

Otology, Neurotology and Skull Base Surgery Book Review

This concise pocket-sized textbook aims to provide a practical reference that clinicians can use in every day otological and skull base practice. The senior author, Derald Brackmann, is one of the leading neurotologists of the modern era and, together with...

Cognitive function is preserved in episodic vestibular disorders

Cognitive deficit in bilateral vestibular failure in particular, but also in unilateral vestibular failure, is well documented. The authors designed this prospective study to determine if deficits in cognition, as well as anxiety and depression, were present in episodic vestibular...

Medicine in the Mountains

This is an easy-to-read paperback with interesting accompanying photographs. Its focus is one of the UK-based teams who have done considerable healthcare work in Nepal. Written by David Hawker, a British anaesthetist, we see the story unfold through his eyes....

Audiology training in Australia

There are many different ways to become an audiologist throughout the world and it is interesting to see how different some of the training routes can be. Wayne Wilson, an Associate Professor and the Head of Audiology at The University...

Audiological approach to treatment of blast-induced tinnitus

Hearing loss and tinnitus resulting from blast waves in the war zone is becoming more common in our clinics. Hamid Jalilvand based in Tehran, shares his experience in audiological rehabilitation and research findings on patients in his clinics with a...