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Laryngeal oedema as a side-effect of tyrosine kinase inhibitor therapy
Tyrosine kinase inhibitors (TKIs) such as Imatinib are increasingly being used to treat haematological and solid malignancies. These agents have revolutionised the treatment of chronic myeloid leukaemia in particular. Although better tolerated than most conventional chemotherapy drugs, multiple side-effects have...
Close monitoring of patients for delayed hyponatremia post-transsphenoidal surgery
he incidence of delayed hyponatremia is 16-28% and usually accounts for unplanned readmission of the patient within 30 days after transsphenoidal surgery. One of the surrogate measures of quality of care adopted by the government and regulatory agencies is 30-day...
A drug to prevent hearing loss caused by ototoxic therapeutics
This editorial briefly highlights the progress made in discovering a compound named ORC-13661, which shows the potential to alter the response of hair cells to ototoxic medication. In the late 1980s, inner hair cells that were lost secondary to noise...
Reducing readmission rates after transsphenoidal pituitary surgery
This retrospective study provides an outpatient care pathway to screen and manage delayed hyponatremia which the study identified as the primary cause of readmission following transsphenoidal pituitary surgery. Of the 303 patients who were studied, 27 were readmitted within 30...
Hearing intervention to prevent dementia
People with hearing impairment have an increased risk of incident all-cause dementia proportional to the severity of loss compared to those with normal hearing. Treating hearing impairment may therefore serve to slow or prevent the onset of cognitive decline. This...
Aided speech auditory brainstem response
Auditory brainstem response (ABR) is commonly used for hearing screening and is considered as one of the important means of objective audiometry. Speech ABR is a relatively new concept and is regarded as a marker of speech encoding at the...
Postoperative complications in OSA patients
This well researched meta-analysis describes the various complications obstructive sleep apnoea (OSA) patients may acquire after surgery. These American reviewers found that OSA patients after non-upper airway operations, were more like to suffer (compared to non-OSA patients), from the following...
What about the older adults?
The authors of this paper propose that significant changes in the delivery of services, including speech and language therapy management of swallowing difficulties, may be required. Among the most common causes of dysphagia in older adults are stroke, progressive neurological...
A cost reducing protocol for magnetic resonance imaging in patients suspected to have acoustic neuroma
Magnetic resonance imaging is the ‘gold standard’ for screening patients suspected to have an acoustic neuroma. However, inappropriate referrals for imaging are not helpful, especially with the growing need to reduce costs. In this study the authors compared two audit...
Association between dysphagia and sarcopenia: implications for assessment of older people
The onset of swallowing difficulties with progressive age is reported to occur in 13-35% of the elderly population. Sarcopenia is characterised by a decrease in muscle mass, strength and function. Sarcopenic dysphagia is a relatively new term. Its prevalence is...
The nice therapist effect: does the therapeutic relationship matter?
Quality of relationships is considered a core component of all speech and language therapy work, yet there is little agreement of what constitutes a therapeutic relationship. This study describes a scoping review to map existing evidence that has investigated this...
