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Can we predict how much benefit patients will get from ESS with a novel monoclonal antibody

Mepolizumab (Nucala) is a humanised IgG1 monoclonal antibody that acts as an IL-5 antagonist. It has been shown to be highly effective in treating severe asthma. It is hypothesised that it will be effective for patients with recalcitrant CRSwNP. This...

Olfactory and gustatory recovery in coronavirus patients after six months

It remains unclear for how long olfactory and gustatory losses persevere in patients with COVID-19. This is a prospective study of 300 patients who lost taste and smell within seven days of contracting COVID-19. The patients were objectively assessed with...

A new treatment for chronic rhinitis

The review paper looks at the efficacy of cryoablation of the posterior nasal nerve (PNN) to treat chronic rhinitis, an increasingly popular method of treating a highly prevalent and morbidity-inducing disease. Five studies were included in the meta-analysis, all dating...

Long-term results for dupilumab are very promising!

Eosinophilic chronic rhinosinusitis (eCRS) is complicated by frequent early and aggressive recurrence of polyps after both medical and surgical treatment regimes. Dupilumab is an anti-IL-4/IL-3 receptor monoclonal antibody and has been previously studied in the SINUS-52 study, with an observation...

A useful adjuvant treatment for SNAC or IP

5-Fluorouracil (5FU) is a topical preparation used in the treatment of various dermatological, ocular and gynaecologic malignant and pre-malignant conditions, and this literature review looks at the efficacy of 5FU in treating inverted papilloma and sinonasal tumours. The authors cite...

A ‘Clear Way’ Forward in Foreign Object Removal – Sterile Single-use Clearway Suction Handle

DTR Medical’s UK manufactured Clearway Suction Handle is the instrument of choice for foreign body removal.

Laryngology & Snoring Issue I

To skip directly to features, click the links below: Welcome from the editor - by Natalie Anne Watson Industry News HPV – why equitable protection matters – by Claire Cameron and Kirsty Roy Papzimeos: a major advance in treating adult...

Balance Disorders: A Brief Overview

Managing balance patients poses a challenge for many clinicians. Vestibular disorders affect a large part of the population and hence present to various specialties including ENT, audiology, neurology and primary care. The healthcare cost of balance disorders and any resultant...

Tinnitus and Sound Sensitivity Case Book

This book, as the title suggests, is full of case studies written by health wprofessionals involving patients who are experiencing tinnitus and/or sound sensitivity. There are 29 different case studies spanning both adults and paediatrics (though mainly adults). Each case...

Which self-reported tinnitus and hyperacusis questionnaires are useful?

Tinnitus and hyperacusis may have very negative psychological side-effects. Due to their subjective nature it is important to have appropriate tools to assess them. In addition to the routine questionnaires such as THI, HQ, ISI, HADS or VAS, the authors...

‘Close’ surgical margin in oral tongue redefined, 2.3mm is as good as 5mm

Gold standard treatment of squamous cell carcinoma (SCC) of the oral tongue remains surgical resection of the primary tumour with negative margins. The primary goal is the complete excision of the tumour with no residual cancer cells left behind. A...