You searched for "chemoradiotherapy"

170 results found

Paediatric hearing following chemotherapy

This study examined the effect of platinum compounds on hearing in 104 children with solid tumours. As would be expected, this group was heterogeneous and included a range of ages, tumour types, chemotherapeutic agents and dosing regimens. Age-appropriate audiometry was...

Risk factors for TORS treatment failure in HPV-related oropharyngeal cancers

HPV-related squamous cell cancers are an increasingly common cause of malignancy in the oropharynx. There is evidence that these cancers are associated with a significantly improved overall survival compared to conventional HPV-negative tumours. The optimal treatment for such cancers is...

Paediatric nasopharyngeal carcinoma

Between 11 and 18% of nasopharyngeal carcinomas (NPC) occur in the paediatric age group but there are no specific management guidelines for this age group. Tunisia is a region with an intermediate incidence of NPC, the authors studied 40 cases...

Are organ-preserving treatment strategies for T3 laryngeal cancers reducing patient survival?

This article presents the 10-year results of a single institution’s treatment of advanced laryngeal cancer. The institution established a protocol based on the Dutch Head and Neck Society consensus document on laryngeal cancer diagnostics and treatment published in 1991. This...

Can smaller cancer centres deliver high quality care for patients with laryngeal cancer?

There is a continuing conflict between treating patients as close to their homes as possible and centralising specialised services, taking into consideration the critical mass and the multi-disciplinary expertise available. This is a report of outcomes in the treatment of...

Role of intranasal steroids after radiotherapy for nasopharyngeal carcinoma

Rhinosinusitis often follows radiotherapy in the treatment of carcinoma of the nasopharynx. The interval and severity may vary with the dose of radiation and stage of the carcinoma. In this randomised, controlled study, patients who developed rhinosinusitis after radiotherapy treatment...

Honey in the management of mucositis

This is a meta-analysis of randomised controlled trials. Despite some limitations, they were able to identify that honey could reduce the severity of radio/chemotherapy induced oral mucositis. They acknowledge that the exact aetiology in the effect of honey is not...

Head and neck radiation and the brain

An increasing number of patients with head and neck squamous cell carcinoma and other lesions are treated with high dose radiotherapy. An increase in survival rates is being reported along with a younger patient demographic. The long-term effects of treatment...

British Skull Base Society Clinical Consensus Document on Management of Head and Neck Paragangliomas (HNPGLs)

All forms of HNPGLs should be managed by a multidisciplinary team (MDT) of core members from skull base otolaryngology, head and neck surgery, clinical genetics, oncology, endocrinology, vascular surgery, radiology and pathology. Extended members include neurosurgery, endocrine surgery, nuclear medicine,...

Structures determining T4a, T4b

This paper for tertiary cancer centre in India attempted to determine whether patients with T4b oral cancers involving the 'masticator space' should be treated with survival intent comparable to T4a cancers. Over a 7-year period, 30 patients with T4b cancers...

Unanswered questions in adult ototoxicity associated with platinum-based chemotherapy

Do the potential side-effects on hearing and tinnitus need to be a ‘necessary evil’ of platinum-based chemotherapy? How strong is our evidence base when offering advice to patients and fellow clinicians? David Baguley and his team from the University of...

Cochlear implantation following radiotherapy treatment of vestibular schwannomas

The authors presented a case report and systematic review assessing the outcomes of patients from cochlear implantation (CI) following radiotherapy treatment for vestibular schwannoma (VS). Outcomes of cochlear implantation in these patients are uncertain due to the combination of both...