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Interleukins, cilia and polyps

Interleukins (ILs) including IL13 (Th2 cytokine) are inflammatory mediators and their role in asthma has been detailed before. This study explores IL13 receptor expression in chronic rhinosinusitis with nasal polyps (CRSwNP). The authors investigate protein and mRNA expression levels of...

Blindness after orthognathic surgery

This is a case report and review of the literature of this rare, but well recognised alarming complication. The authors discuss the possible mechanisms, suggesting that it does not arise from a direct injury to the optic nerve and is...

Scoring system to predict hearing impairment following hemifacial spasm surgical treatment

The authors analysed brain stem auditory evoked potentials prospectively in 100 patients undergoing endoscopic microvascular decompression for management of hemifacial spasm over a period of two years. They then developed a scoring system based on electrophysiological events to predict the...

Increased intensity of treatment: intensity does not improve outcomes

There is a paucity of reports regarding the intensity and appropriate duration of treatment required to improve the language abilities of children with language impairment. This study used direct measures such as the time spent on language, the frequency, number...

Effects of age on neuro-physiological processing of speech at brainstem level

Degenerative changes associated with ageing may affect processing of spectral and temporal cues in speech at cortical and subcortical levels, even though these individuals may have normal audiometric thresholds. These changes are more likely to be picked up by speech...

How common is self-reported dysphagia in the general population?

Healthcare policymakers and commissioners of services often review incidence and prevalence data when deciding on resource allocation. The authors of this paper have capitalised on a large dataset, the Canadian Longitudinal Study on Aging (CLSA), which collects data on over...

Reviewing Meniere’s disease

This was a sizeable literature review (93 references) of not only the office-based treatments for Meniere’s disease but also the various aetiological theories regarding it. They also highlight the amended International Criteria for Meniere’s disease diagnosis (2015), comparing it against...

Vestibular function preservation after minimally invasive paediatric cochlear implantation

This retrospective study analysed results in 24 paediatric patients with low-frequency residual hearing before and after minimally invasive cochlear implantation. The authors define minimally invasive cochlear implantation as a round window insertion of flexible Nucleus CI422, Nucleus CI522, MedEl Flex...

BLA Position Statement - Interview with Mark Watson

Author and interviewer: Stefan Linton, ENT Registrar, Manchester Royal Infirmary. We caught up with Mark Watson, President of the British Laryngology Association, to find out his thoughts on the BLA’s position statement on the use of Gardasil vaccination in the...

Assessment of genetic disorders: congenital sensorineural hearing loss

Severe or profound sensorineural hearing impairment (SNHI) is a common birth defect, affecting approximately 1 in 1000 newborns [1]. SNHI may result from environmental causes or have a genetic basis. The genetic causes can be further subdivided into non-syndromic (isolated...

Effects of air pollution and climate change on the upper airways

Dr Alexander Simidchiev is a specialist in internal medicine, pulmonary medicine and public health. He is the Co-Founder and President of Air for Health, a non-profit organisation aimed at educating medical professionals about the impact of air pollution and climate...

The Ewings and paediatric audiology

Medical historian, Laura Dawes, discusses how Irene and Alexander Ewing were instrumental in shaping paediatric audiology in the first half of the 20th century. Irene and Alexander Ewing were the power couple of audiology in the UK in the mid-20th...