You searched for "genetics"

592 results found

Thalidomide in HHT

An interesting paper from a specialist centre in the Netherlands regarding the use of thalidomide in HHT patients. The St Antonius hospital has 1238 patients with HHT and 1% of these use thalidomide. The aim was to assess the benefits,...

Do I need Google maps in here?

Image guidance surgery (IGS) has grown in popularity. This review article discusses its application in endoscopic sinus surgery (ESS). IGS technology has vastly improved with smaller, more mobile platforms that are easy to set up and use. IGS allows validation...

Two for the price of one - multiple parotid neoplasms

With advancing years come many benefits, but one drawback is the acquisition of parotid (or thyroid) neoplasms. Conventional teaching is that most are benign and slowly enlarge, and not infrequently are found bilaterally as in Warthin’s. Pleomorphic adenomas are also...

Is there time for intraoperative scans?

Intraoperative imaging plays an integral role in orthopaedic surgery during the repair of long-bone fracture. Given the complexity of the facial skeleton, intraoperative imaging has the potential for similar benefits in reconstructive surgery. The objectives of the study were to...

Outpatient injection laryngoplasty

The benefits of a local anaesthetic centred laryngoplasty service in the outpatient environment may interest surgeons and hospital managers alike. This case series looked at patients over a two-year period undergoing local anaesthetic injection laryngoplasty in outpatients. Patient-rated (Voice Performance...

Argh! Facial pain! What to do??

We often come across patients with presentation of facial pain, but unless this is sinugenic in origin, our understanding and management of it can often be found wanting. Craniofacial pain is in fact highly complex and encompasses a wide range...

Balloon dilatation of the eustachian tube: An evidence based review

Eustachian tube dysfunction has long provoked debate among otolaryngologists with wide-spread variation in management. Establishing a safe and effective surgical technique to bring about resolution would be of benefit to those affected, with an estimated incidence of 0.9% in the...

Is there a limitation for excising parapharyngeal tumours transorally?

The parapharyngeal space is a complex anatomical space bounded medially by the oropharynx and laterally by the mandible. It is conceptualised as an inverted pyramid extending from base of skull above to the hyoid bone below. The space is divided...

A new era in the treatment of recalcitrant nasal polyps?

Chronic rhinosinusitis with nasal polyps (CRSwNP) can be difficult to treat effectively in patients with aggressive or recalcitrant disease. Omalizumab (Xolair) is a monoclonal anti-IgE antibody with proven benefits for patients with moderate/severe asthma and CRSwNP, but this study looks...

Tympanostomy tubes outcomes by tympanic quadrants- a meta-analysis

Tympanostomy tube (TT) insertion is one of the most common ENT procedures, resulting in millions of TTs being implanted per annum and occurring complications that need to be addressed. Premature TT extrusion (PTTE) is a well-recognised such complication, affecting almost...

Ultrasound-guided core biopsy of neck lumps as first-line investigative modality supersedes fine needle aspiration cytology in the diagnosis of neck lumps

Ultrasound-guided fine needle aspiration cytology (USFNAC) when applied as initial investigation often proves non-diagnostic, the incidence being as high as 50% in a recent audit. In this study, the authors applied ultrasound-guided core biopsy (USCB) to neck lumps over 1cm...

A more comprehensive management for eosinophilic chronic rhinosinusitis after FESS

In recent years there has been increasing recognition of eosinophilic chronic rhinosinusitis which, in particular, results in persistent symptoms and recurrence of nasal polyps, even after FESS surgery. It therefore calls for measures adjuvant to FESS to stop persistence of...