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211 results found

Molecular and genetic nature of skull base tumours drives management

This article reviews the molecular basis and paradigm shift in the diagnosis and management of skull base tumours. It is now known that the phenotype of meningiomas is influenced by their genotype. Endolymphatic sac tumours are observed in up to...

Maxillofacial and neck surgery in Iraq and Afghanistan

Introduction Over the past 150 years, military personnel wounded in action had a survival rate of approximately 80% [1]. During the current conflicts in Iraq and Afghanistan, those servicemen wounded in action have a 90.4% survival rate [2]. During the...

New biomarkers for salivary gland tumours

Salivary gland tumours comprise approximately 6-8% of head and neck neoplasms. Elevated haematological inflammatory markers, such as neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR), have been shown to be predictive and prognostic in various malignancies. This...

Pituitary tumour associated headaches

This longitudinal cohort study presents data with significant clinical implications for patients with headaches and the clinicians and surgeons who treat them. For the study, patients completed a self-administered survey on headache characteristics on initial presentation and after surgery of...

Two for the price of one - multiple parotid neoplasms

With advancing years come many benefits, but one drawback is the acquisition of parotid (or thyroid) neoplasms. Conventional teaching is that most are benign and slowly enlarge, and not infrequently are found bilaterally as in Warthin’s. Pleomorphic adenomas are also...

Obituary: John Noel Gleave Evans (1934-2022)

John Noel Gleave Evans DLO FRCS, formerly consultant otolaryngologist to St Thomas’ Hospital and Great Ormond Street Hospital for Children, died peacefully at home on 27 March 2022 at the age of 87.

Review of pituitary tumour pathology

This is an excellent review article covering the pathology of pituitary adenomas (PA) as well as rare sellar lesions like lymphocytic hypophysitis that require aggressive treatment. The authors have preserved the 2017 World Health Organization (WHO) classification of PA and...

Botox application for drooling shrinks salivary glands

The large majority of sialorrhoea (drooling) in paediatric patients is managed conservatively. However in severe cases, often where there is associated developmental delay or a motor disorder, medical and surgical techniques can be used to decrease salivary flow. Botulinum toxin...

‘Bare below the elbows’

So it has finally happened. I have reached that stage of reactionary bewilderment known as middle age. As well having my finger nowhere near the pulse of contemporary culture, I am finding the siren charms of BBC Radio 2 and...

Thoughts on war: von Clausewitz revisited

We few, we happy few, we band of brothers; For he to-day that sheds his blood with me Shall be my brother; be he ne’er so vile, This day shall gentle his condition: And gentlemen in England now a-bed Shall...

Acoustic schwannoma regression post-Gamma Knife treatment

In this retrospective study the authors studied the optimal interval following radiosurgery for differentiating between true growth of tumour versus pseudoprogression using serial volumetric data. A total of 118 patients with a median tumour volume of 0.74cm3 at Gamma Knife...

Combined endoscopic and transcutaneous approach for removal of parotid stones

The authors describe a small case series (n=8) of patients with obstructive symptoms from sialolithiasis of the parotid gland. A combined endoscopic and transcutaneous approach was used. The position of the stone in Stensen’s duct was identified by endoscopic transillumination....