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NSC- HHT – a systematic review of intranasal Bevacizumab

This systematic review of 13 studies concerning the use of an anti-angiogenic nasal treatment in the management of epistaxis in HHT patients finds no significant effect. This paper looked at four RCTs, three prospective studies, three retrospective, one case series...

Advances in diagnosis and management of allergic rhinitis

This article reviews advances in the diagnosis and management of allergic rhinitis. Recent advances in the diagnosis of allergic rhinitis include testing of local immunoglobulin E (IgE), urinary test to diagnose aspirin hypersensitivity and optical rhinometry to assess degree of...

The common frontal sinusotomy (Lothrop) and chronic rhinosinusitis

As our understanding of the pathophysiology of CRS evolves, so do our treatment strategies. It is accepted that in many cases, the main role of surgery is to allow better penetration of topical therapies to the sinus cavities. What, then,...

Those little friends in our noses

Human microbiota plays an important role in both health and disease including metabolism, immunomodulation, and a potential role in chronic inflammatory conditions such as chronic rhinosinusitis (CRS). The authors aimed to investigate the sinonasal microbiome using 16S rRNA gene sequencing...

Voice and unilateral vocal fold paralysis

Voice outcomes are the main comparators when managing unilateral vocal fold paralysis (UVP). In a review of the literature, 11 voice indicators are included in 80% of all articles. However, when surgeons were surveyed on their clinical preferences and their...

How the world sees facial palsy patients

This paper from Australia gives an insightful perspective on the impact of facial paralysis on patients, and may explain the well-documented poor quality of life scores in this patient group, particularly those ‘successfully reconstructed’ with surgery. It explores how the...

Current considerations on neural development and hearing loss in young children

The young child’s brain has the ability to change in response to new stimuli, resulting in learning, the foundation of adaptive and intelligent behaviour. For children with hearing loss, a reduction or lack of auditory stimuli can have a ‘lifelong...

Are there any benefits of postoperative antibiotics after endoscopic transsphenoidal surgery for pituitary tumours?

This prospective randomised double-blind multicentre study evaluated whether postoperative antibiotics resulted in improvement in sinonasal quality of life (QoL) compared to placebo in patients undergoing endoscopic endonasal transsphenoidal pituitary surgery. A total of 461 patients were screened for the study...

Vocal cord dysfunction and dysfunctional breathing: an evolving clinical paradigm

Patients frequently present to the ENT department with breathing difficulties. The entity of ‘vocal cord dysfunction’ (also known as paradoxical vocal cord movement, inducible laryngeal obstruction, and many other names) is increasingly well recognised. Ravi Thevasagayam gives us an overview....

Functional Endoscopic Sinus Surgery (FESS) - Part 2

In the first of this two-part series, Martyn Barnes and colleagues discussed indications for functional endoscopic sinus surgery (FESS), the surgical objectives and techniques, patient expectations and the risks of surgery [1]. In this second and final part, the authors...

Reza Band<sup>®</sup> UES Assist Device

Members of the ENT and Audiology News team spoke to Rose Henrichs, Solutiones Vobis and Nick Maris, CEO and President of Somna Therapeutics about the Reza Band device. Nick Maris. Rose Henrichs. What is your involvement in Reza Band? And...

Dupilumab prospective RCT for CRSwNP, a multinational trial of 60 patients with a 16-week CT follow-up

This transcontinental work describes a randomised, double blind, placebo controlled parallel group study over a 16-week period, assessing 60 patients with CRSwNP by CT scan scores. All patients had a four-week period of intranasal corticosteroids followed by randomisation to add...