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272 results found

Hearing loss and Alport syndrome

Alport syndrome (AS) includes a group of hereditary diseases caused by mutations in the COL4A3, COL4A4 or COL4A5 genes. These genes are responsible for the biosynthesis of α3, α4 and α5 collagen IV chains, which are located in the glomerular...

Staphylococcus aureus as a cause of refractory chronic rhinosinusitis

Staphylococcus aureus has long been linked to chronic rhinosinusitis, particularly recalcitrant cases. In this article, Alkis Psaltis describes how newer techniques have shown higher rates of S. aureus infection than were previously thought, and explains how the bacteria are able...

Tinnitus treatment device from concept to commercialisation

Innovation in the field of healthcare is fraught with nearly insurmountable challenges. Bringing a novel product to the market requires a new (patentable) idea that can be reduced to practice, manufactured at scale, and can pass all regulatory barriers. In...

3D printing and sustainability in audiology and ENT

As we try to avoid disposing of equipment that is still functional, we are challenged by company policies that make equipment ‘obsolete’ and no longer supported for repairs. One innovative solution is provided by 3D printing parts that are needed...

The changing landscape for hearing loss therapeutics: novel advances of gene and cell therapies

Recent years have seen advances in hearing loss therapeutics, with novel treatments trialled in humans, and others nearing promising first-in-kind clinical trials. First successful clinical trials for a specific form of genetic hearing loss Very exciting news has emerged in...

The sound of music for adult cochlear implant recipients

Dr Valerie Looi has dedicated her academic career to investigating music perception in people who have cochlear implants, and more recently, the potential of music training for improving their music perception. This article outlines current research relating to music perception...

Long term morbidity of extended medial maxillectomy for inverted papilloma

This Italian review paper looks at five-year morbidity after extended endoscopic medial maxillectomy in 59 patients in a university teaching hospital setting. All patients underwent an extended approach medial maxillectomy for inverting papilloma, this included removal of the entire medial...

ENT bodies stand up for Ukraine

Leading ENT and audiology organisations have made a stand against Russia’s war in Ukraine.

IV dexamethasone versus LA infiltration during paediatric tonsillectomy

Postoperative nausea and vomiting following tonsillectomy is important to control for improved oral intake and satisfaction following surgery. Optimal management is still debated. This team from Beirut conducted a randomised double blind clinical trial comparing the effect of intravenous dexamethasone...

Septoplasty under local and general anaesthetic

This Turkish prospective, non-randomised study compared the quality of life outcomes in 50 patients who underwent local anaesthetic (LA) septoplasty, and 50 patients who underwent general anaesthetic (GA) septoplasty over a six-month period. Quality of life outcomes were measured using...

How can we treat a patient with aural fullness?

Aural fullness is a common complaint that we often come across in many of our otology patients. Management of this condition can be quite challenging. Common differentials include eustachian tube dysfunction, patulous eustachian tube dysfunction, otitic barotrauma, superior canal dehiscence...

Cervicogenic vertigo, a view from the experts

Many readers would be familiar with the term ‘cervicogenic vertigo’ to mean neck-related vertigo or dizziness. In simple terms, this disorder has been defined as dizziness/vertigo caused by neck pain and/or stiffness. By implication, the vertigo/dizziness should resolve by treating...