Journal Reviews
Why do some people get their smell back so quickly after a COVID infection whilst others don’t?
Of course, we are all too familiar with the effect that COVID-19 infection has on our sense of taste and smell, but why do most patients get better whilst, for many, the misery lingers on and on? This paper looks...
QoL post-endoscopic hypophysectomy
This prospective study conducted over four years surveyed more than 300 patients after endoscopic pituitary adenoma resection. The authors used the Anterior Skull Base Questionnaire-35 and the Sinonasal Outcome Test-22, and the scores were analysed for quality of life (QoL)...
Nasopharyngeal versus nasal swabs for COVID-19
This systematic review from Austria compares nasopharyngeal swab (NPS) and PCR test to nasal swabs from the other nasal areas with PCR. After finding 425 articles, using PRISMA guidelines 18 were deemed suitable for comparison. Anterior nasal swabs (ANS) and...
Endoscopic sinus surgery improves Eustachian tube dysfunction
This prospective, multicentre trial from China looked at the improvement in Eustachian tube function after endoscopic sinus surgery. Seventy patients from three tertiary units were included in the study. They all completed the Eustachian tube dysfunction (ETDQ-7) and SNOT-22 questionnaires...
When to operate on a patient without chronic disease?
As ENT surgeons, we spend a lot of time managing chronic rhinosinusitis, so a review and update on the management of the acute disease is always helpful. The standard medical treatment of antibiotics, nasal steroids and nasal decongestants are reported...
Serum biomarkers for CRSwNP
This cross-sectional comparative study looked at 50 patients with nasal polyps who, at the time of diagnosis, also had a blood test evaluating serum total IgE, IL-17 and Pentraxin-3. The study assesses whether these blood markers are useful in the...
Olfactory function and vitamin D
This Turkish prospective study evaluated olfactory function in individuals with primary vitamin D deficiency and the effect of replacement therapy on olfactory function over an eight-month period in 2019. A total of 91 individuals with vitamin D insufficiency were included,...
Olfactory and gustatory recovery in coronavirus patients after six months
It remains unclear for how long olfactory and gustatory losses persevere in patients with COVID-19. This is a prospective study of 300 patients who lost taste and smell within seven days of contracting COVID-19. The patients were objectively assessed with...
Are there any benefits of postoperative antibiotics after endoscopic transsphenoidal surgery for pituitary tumours?
This prospective randomised double-blind multicentre study evaluated whether postoperative antibiotics resulted in improvement in sinonasal quality of life (QoL) compared to placebo in patients undergoing endoscopic endonasal transsphenoidal pituitary surgery. A total of 461 patients were screened for the study...
A new era in the treatment of recalcitrant nasal polyps?
Chronic rhinosinusitis with nasal polyps (CRSwNP) can be difficult to treat effectively in patients with aggressive or recalcitrant disease. Omalizumab (Xolair) is a monoclonal anti-IgE antibody with proven benefits for patients with moderate/severe asthma and CRSwNP, but this study looks...
How safe is sinonasal surgery for the operating surgeon in times of COVID-19?
I’m sure we have all wondered how safe we are in the operating theatre from virus circulating in the room and therefore the risk of subsequent COVID-19 infection. The authors addressed this by measuring the airborne particle concentrations in the...
Olfactory disorders in COVID-19
This Turkish prospective longitudinal observational study evaluated olfactory disorders (OD) and recovery processes in patients with COVID-19 infection at three time points within the first month of diagnosis: time of diagnosis with positive PCR test; time of first negative PCR...
