Journal Reviews

INTERNATIONAL FORUM OF ALLERGY AND RHINOLOGY cover image

The search for the holy grail of rhinosinusitis: another step towards phenotyping in CRS wNP?

7 January 2020 | | Maxillofacial Surgery, Rhinology / Sinus | allergy, asthma, central compartment atopic disease, chronic rhinosinusitis, nasal polyposis

For many years, scientists and clinicians have been trying to understand the infinite variability within the term ‘rhinosinusitis’ using radiology, basic science, epidemiology and then using their insights to solve the riddle of management: how to explain why some patients...

ALLERGY cover

CRSwNP, another monoclonal antibody

1 July 2019 | | Rhinology / Sinus | biomarkers, dupilumab, nasal polyposis, nasal secretions, type 2 inflammation

Interleukins 4, 5 and 13 were shown to be important factors in type 2 inflammation, which characterises chronic rhinosinusitis with nasal polyposis (CRSwNP). In CRSwNP non-responders and those who recur short after-surgery monoclonal antibodies might be an answer. Examples include...