Journal Reviews

Method of delivery: all topical nasal corticosteroids are not made equal

1 July 2018 | | chronic rhinosinusitis, corticosteroid, intranasal spray, nasal polyps, irrigations, paranasal sinuses

There is an increasing body of evidence that the role of surgery for chronic rhinosinusitis is to facilitate the delivery of topical medical treatment – most notably, topical corticosteroids. Two recent studies, one using flow dynamics and another one examining...

Not so innocent, after all: a meta-analysis of the effects of intranasal corticosteroids on growth

1 May 2015 | | allergic rhinitis, androstadienes, beclomethasone, budesonide, fluticasone, glucocorticoid, inhaled glucocorticoids, nasal inhaler, nasal spray, steroids

The use of intranasal corticosteroids has revolutionised the management of allergic rhinitis and rhinosinusitis and there is now significant evidence of their safety. The problem with side-effects is that clinical studies are designed to demonstrate efficacy, but are underpowered to...