The authors retrospectively reviewed the duration of symptom control after intratympanic dexamethasone (IT) injections in 27 patients with Meniere’s disease (MD) over a six-year period. The patients received two IT injections of 3.3mg/ml of dexamethasone one-to-two weeks apart. Eleven patients received a repeat injection. The median follow-up time was 19 months; 85% of their cohort achieved symptom control and four patients did not respond to the treatment. The longest asymptomatic period after IT injection was a median of 19 months (range 11-64 months, IQR:18). The authors did not find any statistical difference between duration of symptom control achieved by the patients and the number of injections they received. The average efficacy of IT dexamethasone in their cohort was for 14.5 months and the authors concluded that patients with autoimmune aetiology were more likely to respond to the steroid injections.
Patients with auto-immune Meniere’s disease more likely to respond to intratympanic steroids
Reviewed by Gauri Mankekar
Duration of symptom control following intratympanic dexamethasone injections in Meniere’s disease.
CONTRIBUTOR
Gauri Mankekar
Department of Otolaryngology-Head Neck Surgery, Louisiana State University Shreveport, Louisiana, USA.
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