Human amnion has historically been the focus of much myth and superstition. To be born with the ‘caul’ intact was considered lucky and the caul was often manufactured into clothing. In 1910 foetal membranes were first used in skin transplantation and since then have been used with great success in almost all sites of the body by most surgical specialties. The authors have written an excellent paper discussing the various uses. They initially outline the anatomy and physiology and go on to discuss the mechanism of its therapeutic effects. This tissue provides an incredible versatile, economical and widely available substrate and is easy to store. This paper is definitely worth reading to appreciate this amazing material and its applications.