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Difficult consultations with HPV-positive oropharnyeal cancer patients

The aetiological role of human papillomavirus (HPV) in oropharyngeal squamous cell carcinoma (OPSCC) is well established, and its incidence has massively increased over the last decade, whilst the incidence of HPV-negative OPSCC is declining. Although we know that HPV-positive OPSCC...

International Federation of Head and Neck Oncologic Societies (IFHNOS): its programmes and impact on head and neck cancer worldwide

In the first article of this edition, we introduce IFHNOS, which has created a major impact on the landscape of head and neck cancer treatment and education over the past quarter of a century by offering a global platform amongst...

OBITUARY: Professor David M Baguley (1961-2022)

Leader, teacher, mentor, scientist, clinician, patient advocate and man of faith: we will not see his like again. The sudden and tragic death of David (Dave) Baguley has left a gap within the national and international audiology and hearing science...

What you need to know about recent advances in genetics of hearing loss in the newborn

Identifying the underlying genetic cause of hearing loss in newborns can improve dramatically the early diagnosis and appropriate intervention. Hearing loss is the most common sensory disorder at birth, affecting approximately two out of 1000 newborns [1]. Congenital impaired hearing...

The role of macrolide antibiotics in chronic rhinosinusitis

The use of long-term antibiotics in the treatment of chronic rhinosinusitis is a contentious issue, not only because of the increasing problem with antibiotic resistance but also because of the potential cardiac risks, including sudden death. In this article, Anders...

2020 Lancet Commission on dementia: a call to action for integrated hearing healthcare

Dr Georgiou’s summary of the 2020 update to the 2017 Lancet Commission underscores the importance of medical and hearing healthcare professionals working together to tackle the modifiable risk factors that affect individuals throughout their lives, to help delay or even...

OBITUARY: Alan Gibb (1919-2020)

Alan Gibb, who passed away on 5 September aged 101, was the Grand Old Man of British Otology. He slipped quietly away at home on Deeside from the long-term consequences of a stroke about two years ago, from which he...

Facial Surgery: Plastic and Reconstructive

Following Professor Cheney’s first popular publication in 1995 on flaps and reconstruction and subsequent second edition, he has now co-edited with Tessa Hadlock a comprehensive two-volume production. They have put together an extensive range of plastic and reconstructive surgery in...

Postoperative pain in septoplasty

This is a prospective Turkish study that looked at factors affecting the postoperative pain response after septoplasty, a common ENT surgical procedure. Sixty patients were included in the study who underwent septoplasty. The authors looked at the influence of demographics...

Hydrogen peroxide and its uses in healthcare

This is an interesting review about the origin and uses of hydrogen peroxide, especially in neurosurgery. However, its uses are ubiquitous and applicable to several medical specialties. When hydrogen peroxide was first discovered in 1818 by Louis Thenard, it had...

Are there any benefits of postoperative antibiotics after endoscopic transsphenoidal surgery for pituitary tumours?

This prospective randomised double-blind multicentre study evaluated whether postoperative antibiotics resulted in improvement in sinonasal quality of life (QoL) compared to placebo in patients undergoing endoscopic endonasal transsphenoidal pituitary surgery. A total of 461 patients were screened for the study...

The future of biologics?

This paper takes a deep dive into how eosinophilia affects the responsiveness of the host to the two monoclonal antibodies mepolizumab and bendralizumab, both of which are active against IL5. We know that eosinophils are attracted and trapped into the...