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The structure and function of DNA

DNA structure and replication Genetic information within multicellular organisms, including man, is stored in molecules of deoxyribonucleic acid (DNA), which reside within the chromosomes of each cell nucleus. A DNA molecule consists of two very long chains, or strands, of...

Evidence based practice in paediatric audiology

Audiology, like most of the health sciences professions, has been working on integrating evidence-based practice principles since the mid-1990s [1]. Professional organisations and regulatory colleges have produced evidence-based clinical practice guidelines, disseminated them to audiologists and collaborated with practitioners to...

From the editor Mar/Apr 2026

Declan Costello, MA, MBBS, FRCS(ORL-HNS),Consultant Ear, Nose and Throat Surgeon, Wexham Park Hospital, Slough, Berkshire, UK. TW / X: @Voicedoctor_uk This year’s calendar is chock full of conferences and meetings, so there will be a lot to cover in the...

Changing perceptions in head and neck cancer management caused by quality of life issues

Sir Felix Semon was an outstanding clinician and exceptional laryngologist. The money raised by donations from his colleagues on his retirement in 1909 was used to establish the London University’s Semon Lecture. Semon’s Obituary in the BMJ, reads: “In Semon's...

Adolescence, drug use and body image

Teenagers are notoriously conscious of how they are perceived by others. Dr Saraiva and colleagues explain how this can lead to problems with substance abuse for both boys and girls, and discuss the different substances they may encounter. Adolescence is...

An update on HPV and the vaccination

In recent years, the role of HPV in the development of oropharyngeal cancers has become apparent. Hannah Fox and Vin Paleri contend that while we may not always be able to cure oropharyngeal cancers, vaccination offers our best hope for...

Leadership in healthcare

There is often a great deal of confusion over the words ‘management’ and ‘leadership’. Sometimes they are used interchangeably. Sometimes they are used to represent opposite ends of a spectrum. Sometimes both are used as collective nouns, or to describe an activity.

Clival chordoma recurrence

Chordomas are generally slow growing and are histologically considered low grade tumours. Their high recurrence rate even after postoperative radiation renders them difficult to treat. This is particularly true for clival chordomas whose deep anatomic location and proximity to vital...

German Society Annual Congress DGHNO-KHC 2024

The 95th Annual Meeting of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery (DGHNO-KHC) was a great success under the forward-looking motto ‘Crossing Borders’

Promoting human rights of deaf communities in low-resource settings

Stigma and misconceptions about deafness are serious impediments for many deaf people to realise rights and potential in some of the most challenging situations globally. Around 430 million people are estimated to live with moderate or higher levels of hearing...

Promoting human rights of deaf communities in low-resource settings

Stigma and misconceptions about deafness are serious impediments for many deaf people to realise rights and potential in some of the most challenging situations globally. Around 430 million people are estimated to live with moderate or higher levels of hearing...

Hearing preservation after Gamma knife in vestibular schwannomas

This retrospective study reports the outcomes of hearing preservation up to three years after Gamma knife radiosurgery for Gardner-Robertson Class I (SDS>70% and PTA <30dB) patients with vestibular schwannomas. The authors report that patients with no subjective or objective hearing...