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The hippo and the nose
Chronic rhinosinusitis with nasal polyps (CRSwNP) leads to histological changes including thickening of the basilar membrane and epithelial proliferation. Molecular mechanisms underlying these changes are still not fully clear. A signalling pathway called the hippo with Yes‐associated protein (YAP) as...Harnessing head and neck cancer genomics for personalised medicine
Luc Morris updates us on the future of cancer diagnosis and treatment, which lies in “personalised oncology”, where specific molecular alterations of each tumour will be identified, and matched with actionable alterations in existing therapies, ushering in the era of...Active middle ear implants and bone-anchored hearing systems
The implantable hearing device market has grown significantly over recent years. But as conventional hearing aids improve and cochlear implant candidacy widens, what is the role for active middle ear implants and bone anchored hearing systems, and how should we...Assessing extended high-frequency hearing
The frequency range of human hearing spans 20 Hz to 20 kHz. In the UK, standard audiometry usually assesses 0.25–8 kHz; the extended high frequencies (EHFs) are those above 8 kHz. The importance of assessing EHF hearing has been increasingly...Why hearing above 8 kHz matters more than you think
This review explores the significance of extended high-frequency hearing loss (above 8 kHz) and why it may be worth doing clinically more frequently. There are many conditions that may hide underneath a normal audiogram, and one of the easiest to...Reduction thyroplasty
Introduction Male to female transgendered patients are referred to ENT for reduction thyroplasty – a procedure to reduce the external appearance of the thyroid cartilage of the larynx, and feminisation of the voice. Reduction thyroplasty, often erroneously called ‘tracheal shave’,...
Growing up smelling the roses
How often do we ask about sense of smell in children? Undoubtedly, the olfactory function is seldom formally assessed in the paediatric population, although evidence exists to suggest its potential links with handicap in children’s learning and development. This large...
